Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions. J Leukoc Biol. 2014;96(3):365-375.Swain L, Wottawa M, Hillemann A, et al. Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of ...
Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition. PLoS One. 2013; 8:e83021.Place TL, Nauseef JT, Peterson MK, Henry MD, Mezhir JJ, Domann FE. Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epi- thelial-to-mesenchymal ...
Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions. J Leukoc Biol. 2014; 96(3):... Lija,Swain,Marieke,... - 《Journal of Leukocyte Biology》 被引量: 20发表: 2014年 Hypoxia-inducible factor-1 (HIF-1) promotes its degr...
上海玉博生物科技有限公司 主要致力于“PIERCEPA116560Anti-HIF Prolylhydroxylase 4 Polyclonal Antibody100 µl4061 100 µl”的生产销售。多年的“PIERCEPA116560Anti-HIF Prolylhydroxylase 4 Polyclonal Antibody100 µl4061 100 µl”生产与销售的经验,与各
we focus on prolyl 4-hydroxylase (P4H), which catalyzes the single most prevalent posttranslational modifcation in humans – the formation of (2S,4R)-4-building hydroxyproline (Hyp) (Figure 1A). Hyp was discovered in gelatin hydrolysates by Emil Fischer (Fischer, 1902; Vickery and Schmidt,...
产品名称:Prolyl 4-hydroxylase subunit alpha-2 ELISA Kit 检测范围:0.78-50 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 选型: 产品规格:96T/48T 96T指可以做94个标本-2个标准对照-84个样本 ...
Gallus gallus prolyl 4-hydroxylase alpha subunit mRNA, 3'UTR, partial sequence 来自 ResearchGate 喜欢 0 阅读量: 17 作者:RI Schwarz,EH Lee,WW Kao,T Simon 摘要: Two factors must be present for primary avian tendon cells to commit 50% of their total protein production to procollagen: ascorbate...
cardiovascular;hy- pertension;prolyl-4-hydroxylase;placenta 【摘要】目的:通过检测脯氨酰-4-羟化酶(P4H)基因在妊 娠高血压综合征(妊高征)患者胎盘中的表达,了解其在妊高 征病理生理机制中的作用.方法:采用半定量RT-PCR技术 检测10例正常妊娠妇女(对照组)及10例中、重度妊高征患 者(妊高征组)胎盘组织P4...
Cellular oxygen is sensed by prolyl-4-hydroxylase domain (PHD) proteins that hydroxylate hypoxia-inducible factor (HIF) alpha subunits. Under normoxic conditions, hydroxylated HIFalpha is bound by the von Hippel-Lindau (pVHL) tumor suppressor, leading to ubiquitinylation and proteasomal degradation. ...
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing...