The research samples were randomly divided into training and testing sets at a ratio of 4:1, with rotation of the test dataset to implement 5-fold cross validation. The initial value of the hyperparameters used in this model was determined by parameter grid search, using 5-fold cross-...
Once the algorithm is trained, it receives in input the exports of countries in a year y (not used during the training stage) and its output is the relatedness of countries with a product. Figure 9 Schematic diagram with the functioning of machine learning algorithms to assess the relatedness...
Seminiferous tubules at stage VII showed a number of irregularities, including the formation of vacuoles and a smaller number of round spermatids arranged in irregular patterns (Figure 2F). In addition, multinucleated cells (arrows in Figure 2F), which appear to be abnormal round spermatids, were...
These metabolites were significantly increased or decreased on AAN progression from early stage to advanced stage. These metabolites could potentially serve as biomarkers for progressive AAN. (F) PCA score plot based on the five metabolites of the control group and AAN group. All statistical ...
In epidemiologic studies, there is evidence that basal-like breast cancers progress very rapidly through the ductal carcinoma in situ (DCIS) stage compared with other cancers [9]. However, many of the DCIS-adjacent stromal tissue studies have been from patients who also have invasive cancers in ...
The CXCR4 expression, overall survival, and the clinical characteristics including age, sex, differentiation degree, tumor size, vascular invasion, lymph node metastasis, TNM stage, and T stage were analyzed for 122 IHCC patients. Short hairpin RNA (shRNA) against CXCR4 was used to disrupt the...
7b), although differences in tumor grade, TNM stage, or lymph node metastasis were not significant (Additional file 2: Table S1). Kaplan–Meier survival analysis showed that CRC patients with high levels of SMARCA4 expression had shorter overall survival than other CRC patients (Fig. 7c). ...
(BMI), and MetS scoring index recorded during the first 3-year stage were used to predict the subsequent occurrence of osteopenia using a non-concurrence design. A concurrent prediction was also performed using the features recorded from the same 3-year stage as the predicted outcome. Machine ...
*Chi-square test or Fisher’s exact test: p < 0.05 indicates a significant relationship among the variables. DDA1 and nuclear p65 staining were positively correlated with pT stage, American Joint Committee on Cancer (AJCC) stage and tumor differentiation in patients with stage II cancer (P < ...
stage III where patients are not candidates for surgical resection or definitive chemoradiation, or metastatic. KEYTRUDA, as a single agent, is indicated for the treatment of patients with metastatic NSCLC whose tumors expr...