Once the algorithm is trained, it receives in input the exports of countries in a year y (not used during the training stage) and its output is the relatedness of countries with a product. Figure 9 Schematic diagram with the functioning of machine learning algorithms to assess the relatedness...
Wilcoxon test was used to compare pathway scores between high tumor stage (stage III/IV) and low stage (stage I/II). Calculating epithelial score and assigning epithelial group using snRNA-seq expression For the epithelial score, we used the markers for the proximal tubule cells and epithelial ...
Seminiferous tubules at stage VII showed a number of irregularities, including the formation of vacuoles and a smaller number of round spermatids arranged in irregular patterns (Figure 2F). In addition, multinucleated cells (arrows in Figure 2F), which appear to be abnormal round spermatids, were...
LysoPE(20:2), cholic acid (CA), chenodeoxycholic acid (CDCA), cystathionine sulfoxide and lysoPC(17:0) were significantly altered in AAN rats at weeks 4, 8 and 12. To identify biomarkers indicative of progressive AAN from early stage to advanced stage during the course of the AAN, a cri...
7b), although differences in tumor grade, TNM stage, or lymph node metastasis were not significant (Additional file 2: Table S1). Kaplan–Meier survival analysis showed that CRC patients with high levels of SMARCA4 expression had shorter overall survival than other CRC patients (Fig. 7c). ...
In epidemiologic studies, there is evidence that basal-like breast cancers progress very rapidly through the ductal carcinoma in situ (DCIS) stage compared with other cancers [9]. However, many of the DCIS-adjacent stromal tissue studies have been from patients who also have invasive cancers in ...
SEMA4B expression was an independent risk factor for the prognosis (OS) of LUAD patients as demonstrated with multivariate Cox regression analysis, which significantly contributed to mortality [HR:1.224; 95% CI: 1.030–1.455;p = 0.022]. T and N stage were independently prognostic for surviv...
s Exact test and identified 29 differentially represented genomic regions (see Additional file10). Second, we used the Survival Predictive Power tool of Nexus in order to determine gains and losses significantly correlated with poor survival in the subset of stage 2 and 3 primary CRCs producing a...
e, pfl in stool metagenomes of stage I/ II, Fnhigh patients with CRC. nFn-no = 19, nFn-low = 34, nFn-high = 58 (NS, not significant, P = 0.0219 for Fn-no versus Fn-high; one-way analysis of variance (ANOVA) with Tukey’s honestly significant differences test...
The research samples were randomly divided into training and testing sets at a ratio of 4:1, with rotation of the test dataset to implement 5-fold cross validation. The initial value of the hyperparameters used in this model was determined by parameter grid search, using 5-fold cross-...