Eldred JA, McDonald M, Wilkes HS, Spalton DJ, Wormstone IM (2016) Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target. Sci Rep 6:24453Eldred JA, McDonald M, Wilkes HS, Spalton DJ, Wormstone IM. ...
关键词: Animals Humans Diabetic Nephropathies Disease Progression Fibrosis Transforming Growth Factor beta Wound Healing Signal Transduction Kidney Diseases DOI: 10.1159/000071736 被引量: 203 年份: 2003 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Karger dx.doi.org NCBI Europe PMC Oxford Univ ...
Liver damage-induced levels of active TGF-β enhance hepatocyte destruction and mediate hepatic stellate cell and fibroblast activation resulting in a wound-healing response, including myofibroblast generation and extracellular matrix deposition. Further evidence points to a decisive role of cytostatic and ...
the potential cargos are internalized by the cells and give rise to early-sorting endosomes (ESEs). The subsequent interactions with organelles, such as the endoplasmic reticulum (ER) and Golgi apparatus, lead to the maturation of ESEs into late-sorting endosomes (LSEs). Following...
1B, C). Additionally, the findings of wound healing and Transwell assessments illuminated that migration and invasion were enhanced when RBM47 was silenced and were repressed after RBM47 overexpression (Fig. 1D, E). The achieved outcomes divulged that upregulation of RBM47 could remarkably ...
A very similar version of this platform has been used to treat topical infections and accelerate wound healing [31]. Induction of osteoarthritis in mice and curcumin treatment All animal studies were approved by the Albert Einstein College of Medicine Institutional Animal Care and Use Committee. ...
Integrin αvβ6 is generally not expressed in adult epithelia but is induced in wound healing, cancer, and certain fibrotic disorders. Despite this generalized absence, we observed that αvβ6 integrin is constitutively expressed in the healthy junctional epithelium linking the gingiva to tooth ename...
The tumor microenvironment (TME) is an important factor that regulates the progression of colorectal cancer (CRC). Cancer-associated fibroblasts (CAFs) are the main mesenchymal cells in the TME and play a vital role in tumor progression; however, the spe
The beta-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts. Signal Transduct Target Ther. 2019;4:63. Article CAS PubMed PubMed Central Google Scholar Lee MJ, Byun MR, Furutani-Seiki M, Hong JH, Jung HS. YAP and TAZ regulate skin wound healing. J Invest ...
(n = 7).F,HEffect of SorCS3 overexpression on wound healing of U87and U251 cells.G,ITranswell assays used to determine the influence of SorCS3 overexpression on the migratory and invasive abilities of U87 and U251 cells.J–LWestern blot analysis of proliferation and EMT associated ...