Nerve growth factor accelerates the early cellular events associated with wound healing. This resembles the classical pattern of cellular responses during the normal process of wound healing. The kinetics for the peak accumulation of each cell type were dependent upon the concentration of NGF injected,...
Lymphatic capillary growth is an integral part of wound healing, yet, the combined effectiveness of stem/progenitor cells on lymphatic and blood vascular regeneration in wounds needs further exploration. Stem/progenitor cell transplantation also emerged as an approach to cure lymphedema, a condition caus...
Abstract The wound repair process is a highly ordered series of events that encompasses hemostasis, inflammatory cell infiltration, tissue regrowth, and remodeling. An important component of normal wound healing is the generation of an inflammatory reaction, which is characterized by the sequential infilt...
Interestingly, thiobarbituric acid reactive substances (TBARS) were elevated in the wound tissues of all the groups, when compared to normal (unwounded) skin tissues. However, in diabetic rats the TBARS levels of both normal and wounded skin tissues were significantly elevated ( P<0.001) when ...
While the body can heal wounds and regrow some tissues, the natural healing process often leads to scarring, which can cause functional limitations in the affected area or lead to cosmetic concerns. Additionally, chronic diseases like obesity or diabetes can complicate wound healing,...
In the wound healing process, the morphology of keratinocytes at the wound edge temporarily changes to a spindle morphology, which is thought to occur due to an epithelial–mesenchymal transition (EMT). Fibroblast growth factor (FGF) 2, also called basic FGF, has the potential to accelerate woun...
After 14 days, the value was almost back to normal. Conclusions During the wound healing process after deep Ⅱ degree scald injury in rats, blood flow increased gradually in accordance with the changes of endothelial cells in granulation tissues. The numbers and structure of endothelial cells ...
Cut-harvest vegetables are subjected to abiotic stress for a short period; therefore, they must be immediately transformed from a normal growth state to an independent unit with independent capabilities (Chen et al., 2023). At the post-harvest stage, wound healing metabolism is intense. ...
This study aimed to investigate the pathway and function of AA during wound healing in a rat pulpotomy model. Sodium-dependent vitamin C transporter (SVCT) 2 and glucose transporter (GLUT) 1 were detected in odontoblasts, endothelial cells, and nerve fibers in normal pulp tissues. SVCT2 and...
Rather, scar tissue forms due to specific mechanisms that occur during the adult wound healing process and are modulated primarily by the inflammatory response at the site of injury. Adult tissue-derived mesenchymal stem cells, which participate in normal wound healing, are trophic mediators of ...