Our results collectively showed the molecular signature of an endothelial/epithelial-mesenchymal (EndMT/EMT) transition-like process, associated with instability of intimal cell junctions and activation of RHOA pathway in the intima and media layers of ascending aorta in BAV patients. We propose that ...
Since the first stage in the HAPaA process has no energy barrier, it applies to both low-temperature interstellar chemistry and high-temperature combustion. Theoretical predictions for HAPaA reaction intermediates and products were validated experimentally using state-of-the-art synchrotron vacuum ultravio...
Candida auris is an emerging multidrug-resistant yeast first described in 2009 that has since caused healthcare-associated outbreaks of severe human infections around the world. In some hospitals, it has become a leading cause of invasive candidiasis. C. auris is markedly different from most other...
Figure 1. Effect of hypoxia on the motility, cell migration and invasiveness of head-and-neck squamous cell carcinoma (HNSCC)-cancer stem cells (CSCs) and non-CSC subpopulations. (a) Representative images of wound-healing assay obtained using IncuCyte at 0, 12 and 24 h after cell scraping ...
A chronic disruption of ATP synthesis through OxPhos would induce, by necessity, a compensatory energy production through the process of substrate level phosphorylation in both the cytoplasm and in the mitochon- dria. As normal mitochondrial function maintains cellular differentiation, the rewiring of ...