Multiple sclerosisAccording to an international study, a drug used to treat multiple sclerosis (MS) also slows the disease's progress. Patients who began taking interferon beta-1a (Avonex, Biogen) within we...
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that results in significant neurodegeneration in the majority of those affected and is a common cause of chronic neurological disability in young adults1,2. Here, to provide insight into the potential mechanisms ...
multiple sclerosisMSSS scorenull genotypegene polymorphismPCR analysisObjective: The aim of our study was to determine the relation of particular genetic variants in selected genes (GSTM1, GSTT1 null genotypes; rs1695 GSTP1; rs10735781 EVI5) to the risk of multiple sclerosis (MS) development ...
Multiple sclerosis: the role of cytokines in pathogenesis and in therapies. Multiple sclerosis, the clinical features and pathological correlate for which were first described by Charcot, is a chronic neuroinflammatory disease with... Amedeo,Amedei,Domenico,... - 《International Journal of Molecular Sc...
To investigate the association between apolipoprotein E (Apo E) genotype in multiple sclerosis (MS) and acute monosymptomatic optic neuritis (ON) in a genetically homogeneous population with a high frequency of the Apo epsilon4 allele. The association between heterozygosity of Apo epsilon4 and the ...
Apo E in multiple sclerosis and optic neuritis: The Apo E-ε4 allele is associated with progression of multiple sclerosis PS, Christiansen M: Apo E in multiple sclerosis and optic neuritis: the apo E-epsilon4 allele is associated with progression of multiple sclerosis. Mult... M Pinholt,J ...
Progression of disability in multiple sclerosis: A study of factors influencing median time to reach an \\{EDSS\\} value Progression of disability in multiple sclerosis: A study of factors influencing median time to reach an \\{EDSS\\} valuedoi:10.1016/j.msard.2012.09.004... Sudarshan ...
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system and a leading cause of neurological disability in young adults. Clinical presentation and disease course are highly heterogeneous. Typically, disease progression occurs
The HLA typing of 100 patients with multiple sclerosis (MS) and their differentiation according to the dynamics of the disease, the type of course and the degree of defect showed the following results: a significant increase in frequency of HLA B7 (P < 0.05), independent of the severity of...
Multiple sclerosisFunctional limitationsHealth behaviorsMultiple sclerosis (MS), a chronic neurological disease typically diagnosed in young adulthood, presents with a wide variety of symptoms, impairments and functional limitations. Given the chronic, unpredictable and long-term nature of this disease, ...