Methods and kits for identifying rapidly progressing lung cancer in a subject are provided. The method includes obtaining a biological sample from the subject and assaying a level of a marker in a biomarker panel in the biological sample where the panel includes at least one biomarker selected ...
Lung cancer is the leading cause of cancer-related death worldwide, and non-small cell lung cancer (NSCLC) accounts for approximately 85% of all types of lung cancers.1NSCLC is typically diagnosed at advanced stages, resulting in a poor 5-year survival rate of less than 15%.2Intratumoral h...
Lung cancer (LC) is the most frequent type of cancer worldwide and the leading cause of cancer mortality [1]. An essential factor in LC deaths is the invasion and metastasis of cancer cells through the circulation or lymphatic systems, Which is a significant cause of mortality in patients [...
This study aims to reveal the potential effect of circNBPF10 on the malignant progression of lung cancer. The expression levels of circNBPF10 in lung cancer tissues and cell lines were detected via r...
Dysregulated metabolism contributes to cancer initiation and progression, but the key drivers of these pathways are just being discovered. Here, we report a critical role for proline catabolism in non-small cell lung cancer (NSCLC). Proline dehydrogenase
Chlamydia pneumoniae infection and risk for lung cancer. Background: We evaluated the relationship of Chlamydia pneumoniae infection with prospective lung cancer risk using traditional serologic markers [microimm... AK Chaturvedi,CA Gaydos,P Agreda,... - Cancer epidemiology, biomarkers & prevention :...
Metabolism is an important part of tumorigenesis as well as progression. The various cancer metabolism pathways, such as glucose metabolism and glutamine metabolism, directly regulate the development and progression of cancer. The pathways by which the cancer cells rewire their metabolism according to th...
MicroRNAs (miRNAs) are regarded as regulators of tumorigenesis and it is known that miR-183-5p is significantly upregulated in non-small cell lung cancer (NSCLC), suggesting it has an oncogenic function in lung cancer. In this study, we found that miR-183-5p could promote lung carcinogenesis...
Treatment for non-small cell lung cancer (NSCLC) has greatly improved in recent years. However, noninvasive early screening for carcinogenesis and progression unclear. The aim of this study was to explore the predictive value of peripheral blood immune c
Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the role of circFLNA in the progression of lung cancer. The target gene of circFLNA was determined by bioinf