Prognostic biomarkers in lung cancer highly depend on tumor histology. For example, many predictive biomarkers in adenocarcinomas also have prognostic significance. Despite recent biomarker discoveries in squamous cell carcinomas, no well-defined prognostic biomarkers have been established. This chapter will...
Many biomarkers have been reported to be independent prognostic factors in patients with lung cancer. KRAS mutations have been frequently associated with negative prognosis, although recent adjuvant chemotherapy trials filed to demonstrate prognostic role of KRAS. Prognostic significance of ERCC1 is ...
This review presents recent data regarding the numerous studies that have been conducted in this field. No marker has yet been proven to offer significant prognostic and predictive information but there is need for further research with metanalyses and new prospective studies. Keywords: Biomarkers, ...
Further, we highlight the potential of modern electronic patient records and advanced data-analyses techniques in this area of research. Non-small cell lung cancer (NSCLC) is a common malignancy and is associated with poor survival outcomes. Biomarkers of systemic inflammation derived from blood ...
Besides, medicinal plants are a huge reservoir of natural products that provide protective effects against lung cancer. Likewise, successful studies of potential phytochemicals in targeting lung-cancer biomarkers have created a novel paradigm for the discovery of potent drugs against lung-cancer. Hence,...
TTC22 as a potential prognostic marker and therapeutic target in pancreatic cancer: Insights into immune infiltration and epithelialmesenchymal transition The mortality rate of pancreatic adenocarcinoma is high, and the effect of traditional treatment is unsatisfactory, thus novel biomarkers are required. Al...
Recently, many studies have been conducted to explore prognostic value of platelet to lymphocyte ratio (PLR) for patients with lung cancer, while the results remain controversial. We collected pretreatment, clinicopathological and follow-up data of 1388
non–small cell lung cancer (NSCLC)p53PTENreceiver operating characteristic (ROC) curveCyclic long noncoding RNAs have recently become major players in cancer biology and can serve as biomarkers for cancer diagnosis and prognosis, and as potential therapeutic targets. We explored circulating LINC00342 ...
Cancer Res 66: 259–266. Article CAS Google Scholar Adams H, Tzankov A, Lugli A, Zlobec I (2009) New time-dependent approach to analyse the prognostic significance of immunohistochemical biomarkers in colon cancer and diffuse large B-cell lymphoma. J Clin Pathol 62: 986–997. Article ...
Yet, the role of MPTDN-related genes in non-small cell lung cancer (NSCLC) remains unrevealed. This study aimed to identify MPTDN-related biomarkers for predicting prognosis and guiding treatment in NSCLC.#Gene expression profiles and clinical information of NSCLC were collected from public ...