programmed cell deathProgrammed cell death (PCD) occurs in the anther during in vivo micro-spore/pollen development. The first hallmarks are detected in the tapetum at meiosis and consist in progressive degeneration of organelles such as mitochondria, as well as DNA degradation into multiple of 180...
The programmed cell death is the potential target for treatment of hepatic fibrosis. The development of small molecule inhibitors for programmed cell death is helpful to slow or even reverse the progression of hepatic fibrosis. Programmed cell death occurs in different cell types and has different ef...
Cell death is predominantly classified into two types: accidental and programmed cell death (PCD) [8]. Accidental cell death occurs without discernible regulatory mechanisms or signals, whereas PCD operates under stringent molecular and signaling control [9]. Since the discovery of apoptosis in 1972,...
The concept of cell death has been expanded beyond apoptosis and necrosis to additional forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death modalities play a critical role in all aspects of life, which are noteworthy fo
Whether programmed cell death occurs in yeast has been controversial, although accumulating evidence suggests this is the case.27 In fact, recent studies suggest that apoptosis in budding yeast is regulated by the proteasome,28 as well as by caspase-related proteases.29 Programmed cell death also ...
Although initial studies suggested that Salmonella induce cell death through an apoptotic pathway, recent studies demonstrate that cell death occurs through a unique caspase 1-dependent mechanism.doi:10.1016/S0966-842X(00)01937-5Lawrence H Boise...
Apoptosis is a type of programmed cell death that often occurs when cells are exposed to stressful conditions. The budding yeast, Saccharomyces cerevisiae, undergoes apoptosis when cultured in particular environmental stimuli including acetic acid, hydrogen peroxide, and ethanol. Just as the human body...
death program (Sperandio et al., 2000). Necroptosis is an alternative receptor-induced form of programmed cell death that is highly regulated and caspase-independent, with morphological resemblance of necrosis (Dunai et al., 2011; Wu et al., 2012). Finally, mitotic catastrophe occurs during ...
is a highly regulated and orchestrated form of cell death that occurs ubiquitously throughout various physiological processes. It plays a crucial role in maintaining homeostasis and the balance of cellular activities. The combination of immune checkpoint inhibitors plus targeted therapies is the first-lin...
VC resembles bone development, which is a pathological process. Medial calcification occurs in close relation with VSMCs that are the primary cell type constituting the arterial wall. Prior researches have established that VSMCs express bone formation-related transcription factors including Msx2, Runx...