Background: No stratification criteria have been established so far for treatment of childhood lymphoblastic T-cell lymphoma (T-LBL). Probability of event-free survival is about 75%, however survival in relapsed patients is very poor. Activating NOTCH1 mutations were reported to be associated with...
Gene expression profile (GEP) studies have provided important insights into the histogenesis and molecular pathogenesis of aggressive T-cell lymphomas. Angioimmunoblastic T-cell lymphoma (AITL) corresponds to T-follicular helper (TFH) lymphocytes and presents consistent deregulation of genes involved in ...
Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma T-cell malignancies have distinct biochemical, immunologic, and clinical features which set them apart from non-T-cell malignancies. In the past, T-cell le... TM Cooper - 《Therapeutics...
Both mRNA expression and CNV of COMMD6 were highest in acute myelocytic leukaemia (AML), meningioma, colorectal cancer and diffuse large B-cell lymphoma (DLBCL) cell lines (Fig. S2A, B). In addition, the methylation status of COMMD6 was highest in lymphocyte malignancies, and lowest in ...
T-cell acute lymphoblastic leukemia (T-ALL) represents a rare and clinically and genetically heterogeneous disease that constitutes 10–15% of newly diagnosed pediatric ALL cases. Despite improved outcomes of these children, the survival rate after relapse is extremely poor. Moreover, the survivors ...
Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acute lymphoblastic leukemia (B-ALL). In children, T-ALL usual... M Ma,W Xiang,J Tang,... - 《医学前...
Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Learn more about the causes, risk factors, symptoms, diagnosis, treatment types, and prognosis for acute lymphoblastic leukemia.
- 《Leukemia & Lymphoma》 被引量: 68发表: 1995年 The impact of CYP3A5*3 on risk and prognosis in childhood acute lymphoblastic leukemia Objectives: Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood; however, little is known of the molecular etiology and environme.....
Th1, Th2, and activated T-cell marker and clinical prognosis in peripheral T-cell lymphoma, unspecified : Comparison with AILD, ALCL, lymphoblastic lymphom... We conducted a retrospective study of treatment outcomes and survival in 120 consecutive, unselected patients with peripheral T-cell non-Hod...
Cell counting kit-8 ccRCC: Clear cell renal cell carcinoma CESC: Cervical cancer DLBC: Lymphoid neoplasm diffuse large b-cell lymphoma DSS: Disease-free survival EMT: Epithelial-to-mesenchymal transition FIGO: International federation of gynecology and obstetrics GBM: Glioblastoma multiforme ...