Objective Glioblastoma is the most common and fatal primary brain tumor in adults. Even with maximal resection and a series of postoperative adjuvant treatments, the median overall survival (OS) of glioblastoma patients remains approximately 15 months. The Huashan Hospital glioma bank contains more ...
When compared with other studies, the proportion of glioma and glioblastoma among brain neoplasms was low whereas pituitary adenoma was high. Mean survival for glioblastoma was similar to other reports; in these patients, the overall therapeutic response is still far from satisfactory. 展开 关键词:...
Glioblastoma is an aggressive form of brain tumor with a poor outcome. Recent advancements using molecular techniques have identified subtypes of glioblastoma that have emerged from the traditional classification. The molecular subtypes are associated with different prognoses and responses to treatment. Both...
IMPORTANCE Glioblastomas and malignant gliomas are the most common primary malignant brain tumors, with an annual incidence of 5.26 per 100 000 population ... A Omuro,LM Deangelis - 《Journal of the American Medical Association》 被引量: 1136发表: 2013年 Cuproptosis‐related classification and ...
For example, one type of brain tumor called a glioblastoma multiforme (GBM) is very aggressive, and patients diagnosed with this tumor typically survive for less than a year. In contrast, a meningioma, which is a tumor derived from the membranes lining the brain, grows much more slowly and ...
Survival curves for astrocytomas, pilocytic astrocytomas, anaplastic astrocytomas, glioblastoma and metastatic tumors were obtained from follow-up studies of the brain tumor patients regardless of therapeutic mode. 展开 被引量: 1 年份: 1995 ...
Preoperative AGR and the PNI may be easy-to-perform and inexpensive indices for predicting OS with glioblastoma. AGR and the PNI could also help in developing good adjuvant-therapy schedules. 展开 关键词: glioblastoma albumin-to-globulin ratio prognostic nutrition index prognosis DOI: 10.2147/OTT...
However, for patients with glioblastomas WHO grade IV this age cutoff is set to 65 years. Knowing the IDH1 mutation status it is likely that patients with anaplastic astrocytomas WHO grade III and no IDH1 mutation will be treated with combined radio- and chemotherapy even if they are older ...
A Novel Berbamine Derivative Inhibits Cell Viability and Induces Apoptosis in Cancer Stem-Like Cells of Human Glioblastoma, via Up-Regulation of miRNA-4284... Glioblastoma (GBM) is the most common primary brain tumor, accounting for approximately 40% of all central nervous system malignancies. Despi...
Glioblastoma (GBM) is a highly lethal brain tumor, refractory to current therapies. Sperm-associated antigen 4 (SPAG4) is a novel cancer marker with unclear roles in GBM progression. This study aimed to explore the specific effects of SPAG4 on the pathogenesis of GBM. We first investigated th...