is the most common form of childhood leukemia.5In ALL, your bone marrow produces too many immature lymphocytes (called lymphoblasts). Lymphocytes are a type of white blood cell that fights bacteria and viruses. Immature lymphocytes can't fight infection. As this fast-growing ...
Ph+cbronic myelocytic leukemia (CML) (21 in chronic phase, CML-CP, 9 in accelerate phase,CML-AP) and 8 followed up patients in blast crisis (CML-BC) were tested by DNA strand breaks (%D value), DNA-aneuploidy, flow cytometry-cell surface antigen expression for CD15 and HLA-DR ratio....
Acute myeloid leukemia (AML) is a heterogeneous malignant disease characterized by bone marrow (BM) infiltration with leukemic blasts [2]. With the implementation of new treatment strategies over the past years, the 5-year survival rate of AML continued to improve and is now around 28%, but t...
Leukemia & LymphomaA r mata J, Grześkowia k‑Melanowska J, Balwierz W, Najbar‑Pabian A and Pawlik‑Niesytto E: Prognosis in acute lymphoblastic leukemia (ALL) in children preceded by an aplastic phase. Leuk Lymphoma 13: 517‑518, 1994....
A simplified system for classification of aggregate incidence and growth pattern in the CFU-c (colony-forming units in culture) assay, allowing simple and reproducible interpretation of test results, was developed and applied to 552 bone marrow samples from 202 patients with acute leukemia. Ninety-...
Obesity has been shown to promote the growth and spread of tumors in a litany of cancers, including leukemia and gastrointestinal cancers. Furthermore, those with emaciated BMI is a critical factor leading to adverse effects and mortality in patients with cancer.1,2,3 Primary e...
1, 2, 3 Recurrent chromosomal rearrangements involving the genes coding for CBFA2 and CBFB are observed in approximately 8% and 4% of patients up to 55 years of age with de novo acute myeloid leukemia (AML), respectively.4 These rearrangements may also be found in patients with therapy-...
805A PROGNOSIS AFTER 3-YEAR SURVIVAL IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model ...
Wolfgang Kern, Torsten Haferlach, Susanne Schnittger, Claudia Haferlach, Ulrike Bacher. Presentation and Diagnosis: Novel Molecular Markers and their Role in the Prognosis and Therapy of Acute Myeloid Leukemia. 2011:, 115-124. /Wolfgang Kern, Torsten Haferlach, Susanne Schnittger, Claudia Ha...
Testin protein (encoded by TES) is expressed in almost all normal human tissues, while low or lack of Testin expression has been found in prostate cancer, endometrial carcinoma, ovarian, breast, acute lymphoblastic leukemia and nasopharyngeal carcinoma [12,13,14,15,16,17]. As a kind of tumor...