(2013). Production of antimicrobial peptides is preserved in aging. Clin. Immunol. 148, 198-205. doi: 10.1016/j.clim.2013.05.015Castaneda-Delgado, J.E.; Miranda-Castro, N.Y.; Gonzalez-Amaro, R.; Gonzalez-Curiel, I.; Montoya-Rosales, A.; Rivas-Calderon, B.; Rivas-Santiago, B. ...
In addition to the discovery of new small-molecule compounds2, alternative drug substances such as antimicrobial peptides (AMPs) have been gaining attention3 because they have multiple mechanisms of action3,4,5,6. However, the demand for such molecules would require efficient and continuous ...
aBacillus spp.produce varied antimicrobial peptides with molecular mass lower than 1.5 kDa and hydrophobic character, however the synthesis of different peptides is under complex genetic regulation and can be induced by modification in culture conditions 杆菌spp.produce各种各样的抗菌肽与分子大量更低比...
Moreover, the diet can modify the GIT microbiota composition and metabolism modulating the production of antimicrobial peptides that can interfere with the growth and the adhesion of pathogens to the intestinal mucosa. The diet can also have a direct effect on the GIT epithelium by modulating ...
29c), further distinguishing this novel antibiotic from other SAL antimicrobial peptides. However, the insensitivity of salivabactin to SpeB proteolysis is probably mitigated by the relatively short-lived sar BGC expression and consequent transient production of salivabactin in vitro (Supplementary Figs...
Production of β-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that are produced by epithelia at mucosal surfaces. Two human beta-defensin... M Mathews,HP Jia,JM Guthmiller,... - 《Infection ...
Antibodies that are specific to the human interferon (IFN)-alpha 1 and -alpha 4 subtypes have been produced by immunizing rabbits with two short synthetic peptides, corresponding to residues 99-111 of IFN-alpha 1 and residues 37-50 of IFN-alpha 4, respectively. The IFN-alpha 1 peptide has...
Antimicrobial peptides(AMPs),a class of polypeptides induced by external conditions,are encoded by specific genes. In the era of facing the issue of "drug resistance" caused by antibiotics,AMPs own huge potential of benefits to mankind a... P Yang,YH Yuan,XL Yang,... - 《Biotechnology Bull...
Cecropin A is a natural antimicrobial peptide that exhibits rapid, potent and long-lasting lytic activity against a broad spectrum of pathogens, thus having great biotechnological potential. Here, we report a system for producing bioactive cecropin A in rice seeds. Results Transgenic rice plants expre...
Antimicrobial peptides(AMPs),a class of polypeptides induced by external conditions,are encoded by specific genes. In the era of facing the issue of "drug resistance" caused by antibiotics,AMPs own huge potential of benefits to mankind a... P Yang,YH Yuan,XL Yang,... - 《Biotechnology Bull...