Antimicrobial peptides and proteins in mycobacterial therapy: Current status and future prospects. Tuberculosis 2014, 94, 363-373. [CrossRef] [PubMed]Padhi, A., Sengupta, M., Sengupta, S., Roehm, K.H., Sonawane, A., 2014. Antimicrobial pep- tides and proteins in mycobacterial therapy: ...
Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the ...
Antimicrobial peptides and proteins (AMPPs) are promising candidates as alternative antibiotics because their mechanism of action is less likely to promote AMR. In the present study, we tested two AMPPs (lysozyme and nisin; 50 and 500 µg/mL) as possible substitutes of gentamicin for boar ...
More than 40 antimicrobial peptides and proteins (AMPs) are expressed in the oral cavity. These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has received extensive attention in recent years for their promise as potential antibiotics. The goal of this review is...
Wang G (2014) Human antimicrobial peptides and proteins. Pharmaceuticals (Basel) 7:545–594. https://doi.org/10.3390/ph7050545 Article CAS Google Scholar Wang G (2015) Improved methods for classification, prediction, and design of antimicrobial peptides. Methods Mol Biol 1268:43–66. https:...
S. Epithelial antimicrobial peptides and proteins: their role in host defence and inflammation. Paediatr. Respir. Rev. 2, 306–310 (2001). CAS PubMed Google Scholar Yang, D., Biragyn, A., Kwak, L. W. & Oppenheim, J. J. Mammalian defensins in immunity: more than just microbicidal....
Animals using toxic peptides and proteins for predation or defense typically depend on specialized morphological structures, like fangs, spines, or a stinger, for effective intoxication. Here we show that amphibian poisons instead incorporate their own molecular system for toxin delivery to attacking pre...
The mode of action of AMPs elucidated to date include inhibition of cell wall formation, formation of pores in the cell membrane resulting in the disruption of membrane potential with eventual lysis of the cell. These peptides also inhibit nuclease activity of both RNase and DNase. ...
pneumoniae capsule polysaccharide limits the interaction of antimicrobial peptides and proteins with the bacterial membrane targets. Article CAS PubMed PubMed Central Google Scholar Luderitz, O. et al. Lipopolysaccharides of Gram-negative Bacteria (Academic Press, 1982). Book Google Scholar Groisman,...
Antimicrobial peptides and proteins (AMPs) are widespread in the living kingdom. They are key effectors of defense reactions and mediators of competitions between organisms. They are often cationic and amphiphilic, which favors their interactions with the anionic membranes of microorganisms. Several AMP...