The use of alternative antimicrobial agents that delay or avoid AMR is therefore urgently needed. This kind of compounds includes antimicrobial peptides and proteins (AMPPs), which are a diverse group of molecules produced by a wide variety of organisms (prokaryotes and eukaryotes) as their first ...
Antimicrobial proteins and peptides in human lung diseases: A friend and foe partnership with host proteases. Biochimie 2016, 122, 151-168. [CrossRef] [PubMed]Lecaille F, Lalmanach G, Andrault PM. Antimicrobial proteins and pep- tides in human lung diseases: a friend and foe partnership ...
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all multicellular organisms. These proteins can have broad activity to directly kill bacteria, yeasts, fungi, viruses and even cancer cells. Insects and ...
Antimicrobial peptides and proteins (AMPPs) are promising candidates as alternative antibiotics because their mechanism of action is less likely to promote AMR. In the present study, we tested two AMPPs (lysozyme and nisin; 50 and 500 g/mL) as possible substitutes of gentamicin for boar semen ...
More than 40 antimicrobial peptides and proteins (AMPs) are expressed in the oral cavity. These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has received extensive attention in recent years for their promise as potential antibiotics. The goal of this review is...
Animals using toxic peptides and proteins for predation or defense typically depend on specialized morphological structures, like fangs, spines, or a stinger, for effective intoxication. Here we show that amphibian poisons instead incorporate their own molecular system for toxin delivery to attacking pre...
S. Epithelial antimicrobial peptides and proteins: their role in host defence and inflammation. Paediatr. Respir. Rev. 2, 306–310 (2001). CAS PubMed Google Scholar Yang, D., Biragyn, A., Kwak, L. W. & Oppenheim, J. J. Mammalian defensins in immunity: more than just microbicidal....
pH dependent antimicrobial peptides and proteins, their mechanisms of action and potential as therapeutic agents Pharmaceuticals (Basel), 9 (4) (2016) Google Scholar Mansbach et al., 2020 R.A. Mansbach, I.V. Leus, J. Mehla, C.A. Lopez, J.K. Walker, V.V. Rybenkov, N.W. Hengartn...
The mode of action of AMPs elucidated to date include inhibition of cell wall formation, formation of pores in the cell membrane resulting in the disruption of membrane potential with eventual lysis of the cell. These peptides also inhibit nuclease activity of both RNase and DNase. ...
Antimicrobial peptides and proteins (AMPs) are widespread in the living kingdom. They are key effectors of defense reactions and mediators of competitions between organisms. They are often cationic and amphiphilic, which favors their interactions with the anionic membranes of microorganisms. Several AMP...