ID: 109: Pro-inflammatory cytokines and chemokines in HPV-positive cancer cellsInflammation is a critical component of tumorigenesis. Tumor microenvironment participates in the neoplastic process fostering proliferation, survival and migration. Virus-induced tumors, like HPV-induced Squamous Cell Carcinomas,...
Protein studies is revealed that JIA FLS release pro-inflammatory cytokines and chemokines, including IL-4, IL-6, IL-17, CXCL1, and CXCL6, and lose expression of important regulator signals, such as IL-10 and TIMP2. Of the 84 proteins differentially expressed between controls and JIA in ...
Interferon gamma plus lipopolysaccharide (LPS) or tumor necrosis factor α alone are known to induce classical macrophage activation that is characterized by an increased secretion of pro-inflammatory cytokines and chemokines (such as interleukin (IL)-1β), an augmented production of inducible nitric ...
What are Pro-Inflammatory Cytokines? Cytokine is a general term used for small secreted proteins that are key modulators of inflammation. Cytokines are produced in response to invading pathogens to stimulate, recruit, and proliferate immune cells. Cytokines includes inte...
Cytokines are produced in response to invading pathogens to stimulate, recruit, and proliferate immune cells. Cytokines includes interleukins (IL), chemokines, interferons, and tumor necrosis factors (TNF). Cytokines are subdivided based on the nature of the immune resp...
Although Stat4 has been most extensively investigated as a critical mediator for several pro-inflammatory cytokines and chemokines such as IL-12 and type I interferon in T lymphocytes, it was unknown whether it had any role in vasculogenesis. Several studies have provided clues that the Stat4-...
Lipid-toxicity-induced hepatocyte injury recruits monocyte-derived macrophages by releasing pro-inflammatory cytokines and chemokines, thus accelerating the progression of NAFLD to NASH [18]. Direct and indirect coculture of hepatocytes and macrophage cell lines in the same media have been used to ...
TLRs are highly conserved proteins and have leucine-rich repeats (LRR) in the extracellular part and Toll/IL-1 receptor (TIR) within cytoplasm, which is capable of initiating the innate immune response (Taverna et al.2022). Interaction between TLRs and HMGB1 triggers cytokines and chemokines sec...
What are Pro-Inflammatory Cytokines? Cytokine is a general term used for small secreted proteins that are key modulators of inflammation. Cytokines are produced in response to invading pathogens to stimulate, recruit, and proliferate immune cells. Cytokines includes inte...
Cytokines are produced in response to invading pathogens to stimulate, recruit, and proliferate immune cells. Cytokines includes interleukins (IL), chemokines, interferons, and tumor necrosis factors (TNF). Cytokines are subdivided based on the nature of the immune resp...