The polymorphisms of the PRNP gene influence the susceptibility to scrapie in goats. In this study, caprine PRNP gene was analysed in a total of 249 individuals from three main indigenous goat breeds of Turkey: Anatolian Black, Angora and Kilis. We focused on the Anatolian Black breed, ...
Gene ID: 5621 种属 Homo sapiens 基因序列编号: NM_000311.5 基因描述 Homo sapiens prion protein (PRNP), transcript variant 1, mRNA DNA编码区: atggcgaaccttggctgctggatgctggttctctttgtggccacatggagtgacctgggc ctctgcaagaagcgcccgaagcctggaggatggaacactgggggcagccgatacccgggg cagggcagccctggaggcaaccgctacccacct...
Gene SummaryThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 ...
This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, ...
PRNP 基因 PRNP 基因(Prion Protein Gene)是编码朊蛋白的基因[11]。不同种属的哺乳动物 中的PRNP 基因的初始转录子在结构上存在差异,因此 PRNP 基因可以分为两类, 一类是如仓鼠、人类等,由两个外显子和一个内含子组成;另一类如牛、羊、小鼠 等, 是三个外显子和两个内含子组成[12], 人的 PRNP 基因...
Scrapie is a transmissible spongiform encephalopathy affecting sheep and goats. The prion protein-encoding gene (PRNP) plays a crucial role in determining susceptibility and resistance to scrapie. At the European level, surveillance of scrapie is essenti
品牌:沪震生物产地:中国/上海 保存条件:-20°C纯度规格:> 99% 产品类别:重组蛋白 货号:HZ505509TP用途范围:Positive Control; Immunogen; SDS-PAGE; WB 规格:10ug 50ug 100ug 200ug 1mg Recombinant Prion Protein (PRNP) Sequence Information Species:Human Gene ID:9128 ...
The PRNP gene codes for prion protein, which is a protein that causes disease (PrP). From: Viral, Parasitic, Bacterial, and Fungal Infections, 2023 About this pageSet alert Also in subject areas: Agricultural and Biological Sciences Biochemistry, Genetics and Molecular BiologyDiscover other topics...
Supplementary data: Analysis of single nucleotide polymorphisms of PRNP gene in twenty-four ethnic groups of India Mainak Sengupta, Amrita Chakraborty, Indian Genome Variation Consortium and Kunal Ray J. Genet. 89, 247–251 Table 1. Allele and genotype frequency of integenic SNP rs2756271...
We report here a case of Gerstmann-Str¤ussler-Scheinker (GSS) disease with a new mutation at the codon 232 (Met to Thr) of the PRNP gene. This case was characterized by PrP-immunopositive kuru and multicentric plaques; these plaques were also seen in the cerebral cortex, hippocampus and...