Gene ID: 5621 种属 Homo sapiens 基因序列编号: NM_000311.5 基因描述 Homo sapiens prion protein (PRNP), transcript variant 1, mRNA DNA编码区: atggcgaaccttggctgctggatgctggttctctttgtggccacatggagtgacctgggc ctctgcaagaagcgcccgaagcctggaggatggaacactgggggcagccgatacccgggg cagggcagccctggaggcaaccgctacccacct...
The polymorphisms of the PRNP gene influence the susceptibility to scrapie in goats. In this study, caprine PRNP gene was analysed in a total of 249 individuals from three main indigenous goat breeds of Turkey: Anatolian Black, Angora and Kilis. We focused on the Anatolian Black breed, ...
An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] [中文简述(自动翻译):] 由该基因编码的蛋白质是一种膜糖基 - 锚定的糖蛋白倾向...
Gene SummaryThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 ...
PRNP 基因 PRNP 基因(Prion Protein Gene)是编码朊蛋白的基因[11]。不同种属的哺乳动物 中的PRNP 基因的初始转录子在结构上存在差异,因此 PRNP 基因可以分为两类, 一类是如仓鼠、人类等,由两个外显子和一个内含子组成;另一类如牛、羊、小鼠 等, 是三个外显子和两个内含子组成[12], 人的 PRNP 基因...
31、[25]xiao-long d,run w,lei l,et al.expression patterns ofprnp geneduring chicken embryo development[j].asian j anim vet adv,2012,7(2):199-204. 32、[26]redecke l.,meyer-klaucke w.,koker m.,et al.comparative analysisof the human and chicken prion protein copper binding regions ...
The structure of cellular prion proteins encoded by the prion protein gene (PRNP) impacts susceptibility to transmissible spongiform encephalopathies, including chronic wasting disease (CWD) in deer. The recent emergence of CWD in Northern European reind
Gene SummaryThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 ...
This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, ...
Scrapie is a transmissible spongiform encephalopathy affecting sheep and goats. The prion protein-encoding gene (PRNP) plays a crucial role in determining susceptibility and resistance to scrapie. At the European level, surveillance of scrapie is essenti