Primary open-angle glaucoma: pathophysiology and treatment. Lancet 2004;364(9442):1311-2.Jannis Kountouras,Christos Zavos,Dimitrios Chatzopoulos.Primary open-angle glaucoma: pathophysiology and treatment[J]. The Lancet .2004(9442)Kountouras J,Zavos C,Chatzopoulos D.Primary open-angle glauco ma:...
Primary open-angle glaucoma (POAG) is described distinctly as a multifactorial optic neuropathy that is chronic, progressive, and irreversible, with a characteristic acquired loss of optic nerve fibers. [1, 2] Such loss develops in the presence of open anterior chamber angles, characteristic visual...
Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible blindness worldwide, but typically remains asymptomatic until very severe. Open-angle glaucoma comprises the majority of case...
Glaucoma is a common, complex, heterogenous disease and it constitutes the major cause of irreversible blindness worldwide. Primary open-angle glaucoma (POAG) is the most common type of glaucoma in all populations. Most of the molecular mechanisms leading to POAG development are still unknown. Gene...
About 5% of primary open angle glaucoma (POAG) is currently attributed to single-gene or Mendelian forms of glaucoma (ie glaucoma caused by mutations in myocilin or optineurin). Mutations in these genes have a high likelihood of leading to glaucoma and are rarely seen in normal subjects. Other...
There is extensive evidence that there is a genetic component to developing primary open-angle glaucoma (POAG). Unraveling this genetic component might clarify the pathophysiology of the disease and greatly assist in treatment and prevention of visual loss of many thousands of individuals. Linkage and...
However, in primary open angle glaucoma (POAG), the angle appears normal and the cause for the increase in outflow resistance through the outflow pathway, especially the cell- and connective tissue-filled lattice work of the TM, has remained obscure (5). Figure 1 Normal fluid movement in ...
To compare the intermediate-term efficacy of PRESERFLO (PF) MicroShunt implantation with trabeculectomy (TE) in patients with primary open-angle glaucoma, focusing on longitudinal changes of functional and structural parameters. Methods This retrospective comparative study included 104 eyes of 104 patients...
Section 2 deals with primary open-angle glaucoma. Section 3 describes angle-closure glaucoma. Section 4 describes seconda... CD Phelps - 《Archives of Ophthalmology》 被引量: 5发表: 1977年 New Concepts in Steroid Glaucoma In this article, we discuss the pathophysiology underlying intraocular ...
Primary open-angle glaucoma: pathophysiology and treatment. By - Jannis Kountouras, Christos Zavos, Dimitrios Chatzopoulos J Kountouras,C Zavos,D Chatzopoulos - 《Lancet》 被引量: 63发表: 2004年 Impaired Complex-I-Linked Respiration and ATP Synthesis in Primary Open-Angle Glaucoma Patient Lymph...