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Cell–cell and cell–matrix interactions, cell polarization, and 3D organization cannot be studied using monolayer cell lines (Kim, 2005; Yamada et al., 2007). The use of 2D cocultures, where two or more different populations of cells are grown within one culture, can give more insights ...
primary cell 原电池 | 原生电池 | 一次电池 | 初生细胞 primary source 一次文献 | 一次光源 | 主电源 | 直接资料 primary production 初级生产 | 第一级生产 | 第一性生产量 | 第一产业 Primary Tumor 原发肿瘤 | 初生肿瘤 | 原发瘤 | 肿瘤原发灶 同根词 词根:prima adj. prime 主要的;最...
ranges were largest in PAAD (0.29–0.76), LUSC (0.32–0.79), and LIHC (0.26–0.72), which likely reflect the amount of heterogeneity within each tumor type and suggest that some primary tumor samples are well matched with cell lines, while others may lack representative cell line models. ...
F. Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 85, 2161–2165 (1988). Article Google Scholar Chen, M. B....
Interleukin-5 (IL-5) is an inducible T-cell derived cytokine with remarkable specificity for the eosinophil lineage. It is controlled at the level of transcription and regulation of the gene is an obvious target for therapy of eosinophil-dependent allergic disorders such as asthma, eczema and rhi...
PDGFR signaling regulates cell growth and survival, transformation, migration and wound healing [26]. Several reports document a change in the expression level of the alpha form of PDGFR (PDGFRα) compared to normal OSE cells and that this expression is associated with high tumor grade, high pro...
Primary Cells from their source organ tissue and media optimized for each individual cell type (and always in stock).
and 9 proteins underexpression as compared with L02 cell line.The dephosphorylated protein 17175Da expressed higher in L02 cells,but the phosphorylated protein 17255Da expressed higher in SMMC7721cells.Conclusion The overexpressed and underexpressed proteins in protein profiling could be candidate ...
It has become evident that intra-tumor heterogeneity of breast cancer impact on several biological processes such as proliferation, migration, cell death and also might contribute to chemotherapy resistance. The expression of Receptor Tyrosine Kinases (RTKs) has not been analyzed in the context of in...