Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Primary biliary cholangitis (PBC) is a rare immune-mediated disease, commonly affecting women in their 40s, and ultimately progressing to liver failure. The incidence and prevalence of the disease are increasing worldwide, possibly due to better diagnostic tools. This review will focus on its ...
Primary biliary cholangitis (PBC, formerly known as primary biliary cirrhosis) is an uncommon cholestatic liver disease characterized by immune-mediated destruction of biliary epithelial cells. PBC is female preponderant and typically presents in the fifth or sixth decade of life. The clinical presentat...
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well-orchestrated immune reaction, both innate and adaptive, against mitochondrial antigens that specifically targets intrahepatic bi...
Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to clarify the pathogenesis of PBC and explore the occurrence of early events. Herein, we
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其病变由自身免疫异常引起,最终可能进展为肝硬化和肝衰竭,该病具有遗传倾向。本文主要的参考文献为中华医学会肝病学分会《2021原发性胆汁性...
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病。
We describe the first well documented patient with an overlap between the three autoimmune liver diseases, primary biliary cholangitis, autoimmune hepatitis and primary sclerosing cholangitis. The rare overlap between PBC and PSC has been reported in only 11 patients in the literature to date [[5],...
Primary Biliary Cholangitis (PBC) Is Associated With Significant Mortality and Health Care Utilization (HCU) in Medicare Population: 959Younossi, Zobair M.Stepanova, MariaYounossi, IssahNader, FatemaRacila-, AndreiOfficial journal of the American College of Gastroenterology | ACG...
OBJECTIVE: Observational studies have shown a higher prevalence of Sjogren's syndrome (SjS) in patients with primary biliary cholangitis (PBC) than in the healthy population, but whether this correlation is causal needs further confirmation. This study aimed to investigate the bidirectional causal ...