Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Primary biliary cholangitis (PBC) is a rare chronic autoimmune-mediated cholestatic liver disease involving medium and small bile ducts that can lead to liver fibrosis and cirrhosis. To date, the pathogenesis of PBC remains elusive, and there is currently no curative medical treatment. Computed ...
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其病变由自身免疫异常引起,最终可能进展为肝硬化和肝衰竭,该病具有遗传倾向。本文主要的参考文献为中华医学会肝病学分会《2021原发性胆汁性...
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well-orchestrated immune reaction, both innate and adaptive, against mitochondrial antigens that specifically targets intrahepatic bi...
Primary biliary cholangitis (PBC, formerly known as primary biliary cirrhosis) is an uncommon cholestatic liver disease characterized by immune-mediated destruction of biliary epithelial cells. PBC is female preponderant and typically presents in the fifth or sixth decade of life. The clinical presentat...
Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to clarify the pathogenesis of PBC and explore the occurrence of early events. Herein, we
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病。
Primary Sclerosing Cholangitis Primary sclerosing cholangitis(PSC) is a chronic cholestatic disease of the liver comprising progressive inflammation, fibrosis, and stricturing of the intrahepatic and extrahepaticbile ducts. Complications include recurrent cholangitis,biliary cirrhosis, and end-stage ...
Christelle Huguet, head of R&D at Ipsen, said in a statement that Iqirvo is a “much-needed treatment option” for patients with primary biliary cholangitis (PBC) and is the first new drug for this condition in nearly a decade. “For a significant number of people living with PBC,...
Primary biliary cholangitis 来自 学术范 喜欢 0 阅读量: 77 作者: P Albert 摘要: Primary cholangitis (cirrhosis) is a chronic cholestatic disease with an unquestionable female predominance. It is characterised by inflammation of the small and medium size bile ducts, and can eventually progress to ...