There are several primary sequence databases available that are widely used in the field of bioinformatics. The three main primary databases are GenBank at the National Center for Biotechnology Information (NCBI), the DNA Database of Japan (DDBJ), and the European Molecular Biology Laboratory (EMBL...
Therefore, present study aims for analysis of primary, secondary and tertiary structure of disease resistance protein RGA4 of Zea Maize using bioinformatics tools and proposing the best 3D model after evaluating various parameters. Methods: Primary structure analysis was done by ProtParam, Secondary ...
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We downloaded primary and secondary sequences of all 303,524 proteins of the PDB protein databank. Eliminating the duplicates and proteins of residue length less than 30, we have got a non redundant database of 80,592. We developed a search algorithm FIND-SIM to find similar primary sequence...
Neutrophils are the most abundant human white blood cell and constitute a first line of defense in the innate immune response. Neutrophils are short-lived cells and thus the impact of organismal aging on neutrophil biology, especially as a function of bi
We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with...
Gramm,J. - 《IEEE/ACM Transactions on Computational Biology & Bioinformatics》 被引量: 37发表: 2004年 PAMA:: A FAST STRING MATCHING ALGORITHM. String matching is a fundamental operation in computer science, and its performance has great impact on many applications including database query, text ...
visualisation and integrated discovery” (DAVID) Bioinformatics Resources 6.8 (https://david.ncifcrf.gov/)31,32. The tool DAVID was chosen to: (1) identify major gene groups (functional classification); (2) to elucidate enriched annotation terms (functional annotation chart and clustering, respecti...
Metastatic spread involves tumour cell detachment from a primary tumour, colonization of a secondary tissue and growth in a hostile environment1,2. Advanced metastatic tumours are frequently able to resist aggressive treatment regimes6. Despite the many efforts to understand these phenomena3,7,8,9, ...
Glioblastoma (GBM) is the most common malignant brain tumor in adults, which remains incurable and often recurs rapidly after initial therapy. While large efforts have been dedicated to uncover genomic/transcriptomic alternations associated with the recu