Also, syndromic patients, for example those with Williams syndrome, may suffer from a generalized aortopathy, which triggers increased arterial stiffness and hypertension. This review summarizes the state-of-the
Secondary hyperaldosteronism is most frequently associated with increases in activity of the renin-angiotensin system, usually resulting from renovascular disorders; hypertension and complications are usually more severe. High levels of plasma renin activity and elevated, suppressible aldosterone levels are ...
Secondary hypertension is elevation of blood pressure above normal for the age due to a clinically detectable preceding cause. Common primary causes of secondary high blood pressure are, renal diseases, endocrine diseases, coarctation of aorta, pregnancy, and medications.Chronic and acute renal failures...
Primary aldosteronism (PA) is a common cause of secondary hypertension and is associated with worse cardiovascular outcomes. The elevated aldosterone in PA leads to left ventricular (LV) remodeling and dysfunction. In recent decades, clinical studies have demonstrated worse LV remodeling including increas...
Study participants were patients of any age who presented to a primary, secondary or tertiary care services with unknown causes of chronic dyspnoea (duration ≥1 month). The main outcome of interest was the use and diagnostic accuracy of an algorithmic approach to the assessment of dyspnoea. ...
(within brain parenchyma) or extraaxial (intraventricular, subarachnoid, subdural, and epidural spaces). Primary brain injury is a complete and nonreversible event that triggers a series of subsequent neuro-electro-chemical cascade events (secondary injury) that ultimately end in neuronal cel...
IHA and APA are the most important causes of PA. 2. How common are these disorders? The most common manifestation of excess aldosterone secretion is hypertension. Cross-sectional and prospective studies indicate that up to 12% of the hypertensive population may have PA. 3. Aside from ...
At entry and during 20 years follow-up, all signs of kidney disease, secondary hypertension, or increase in blood pressure were investigated. Records of patients with a serum creatinine value 130 μmol/l at any time during the observation period were thoroughly studied to ascertain the cause of...
As a part of the formative phase of an implementation research study, we conducted a needs assessment to define short- and long-term needs and opportunities for hypertension services within the public health system. Methods We conducted a multi-method, multi-level assessment of needs related to ...
Out of 334 evaluated patients, 9.3% had an underlying vascular etiology. Independent predictors of the vascular etiology included: age < 46 years, no history of hypertension and coagulation disorders, lobar hemorrhages, and presence of significant perilesional edema. We used these criteria and ...