Severe hypertension in young patients presents a significant diagnostic dilemma, and treatment can often be codified. Therefore, it is crucial to diagnose these cases for probable secondary hypertension. Common
Hypertension can affect anyone in the world. That shows how common this condition really is. Hypertension happens when the body's smaller blood vessels narrow, which causes the blood to have a lot of extra pressure against the vessels wall, which makes the heart work harder. High blood ...
The rhinoviruses, which are RNA viruses that infect the respiratory epithelium, have long been known as common cold viruses, but they also are important causes of exacerbations of chronic bronchitis and asthma. More recent data suggest that rhinoviruses may also be associated with bronchiolitis in ...
Background: Pulmonary hypertension may result in significant morbidity and mortality after pediatric cardiac surgery. The objective of this study was to determine the incidence and outcome of severe pulmonary hypertension, defined as a ratio of pulmonary to systemic arterial pressure equal to or greater...
et al. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature 586, 763–768 (2020). Article ADS CAS PubMed PubMed Central MATH Google Scholar Codd, V. et al. Polygenic basis and biomedical consequences of telomere length variation. Nat. Genet. 53, 1425–1433 (2021)....
Objective: Primary aldosteronism (PA) is the most common form of secondary and curable hypertension. Different germline and somatic mutations are found in aldosterone producing adenoma (APA) and familial forms of the disease, while the causes of bilateral adrenal hyperplasia (BAH) remain largely unkno...
Obesity causes severe healthcare problem worldwide leading to numerous diseases, such as cardiovascular diseases and diabetes mellitus. Previous Genome-Wide Association Study (GWAS) identified an association between a single nucleotide polymorphism (SNP) rs7138803, on chromosome 12q13 and obesity in Europ...
the higher ratio of body surface area to body volume in mice leads to faster heat loss and hypothermia [7]. Small body size of mice also causes physical problmes. For example, endotracheal intubation and ventilation of this species are demanding tasks, and many veterinary anesthesia monitoring ...
gene sets with transcriptome datasets from human patients with chronic thromboembolic pulmonary hypertension (CTEPH) led to the identification of more than 50 genes whose expression levels correlated with the severity of right heart disease, including multiple matrix-regulating and secreted factors. These ...
SH3RF1 as regulators of synaptic growth responses, it is a novel nexu slinking activity of TGF-β and JNK signaling via TAK1 (TGF-β–activated kinase 1), a JNK kinase kinase (JNKKK) essential for synaptic overgrowth in Rab8 mutants53, this may be one of the causes of frontotemporal ...