蛋白质二级结构的预测是揭示其三维结构和功能的关键中间步骤。MCP(Multi-Component learning machine to Predict protein secondary structure)是一种多组分学习机器,用于预测蛋白质的二级结构。该方法基于大量的已知蛋白质序列和实验测定的二级结构信息进行训练,通过学
PREDICT PROTEIN-PROTEIN AND DOMAIN-DOMAIN INTERACTIONSprotein and domain interactionsgene fusion eventsmultiple sequence alignments (MSA)Publication » PREDICT PROTEIN-PROTEIN AND DOMAIN-DOMAIN INTERACTIONS.doi:http://dx.doi.org/Raja JothiTeresa M. Przytycka...
We detected GO term enrichments for “G protein-coupled receptor (GPCR) activity” and “GPCR signaling pathway” (Fig.3). These enrichments resulted from 71 GPCR-related PPIs with 16 uniqueOphiocordycepsproteins (Supplementary FileS1). All but two receptor proteins in these PPIs carried the PFA...
Lambda Predict Protein(LPP)是一种常用的蛋白质亚细胞定位预测工具,通过分析蛋白质序列的特征,利用机器学习算法预测蛋白质在细胞内的定位。LPP在蛋白质组学研究中具有广泛的应用,能够帮助研究人员快速准确地预测蛋白质的亚细胞定位,并为后续的功能研究和药物设计提供重要线索。同时,LPP的优化和改进研究也在不断进行,为蛋...
摘要: Publication » PREDICT PROTEIN-PROTEIN AND DOMAIN-DOMAIN INTERACTIONS.关键词: protein and domain interactions gene fusion events multiple sequence alignments (MSA) 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 Wiley dx.doi.org ResearchGate ResearchGate (全网免费下载) ...
Protein-protein interactions are facilitated by a myriad of residue-residue contacts on the interacting proteins. Identifying the site of interaction in the protein is a key for deciphering its functional mechanisms, and is crucial for drug development. Many studies indicate that the compositions of ...
通过一种新颖的迭代方法,我们开发了一种基于知识的打分函数(ITScore),用于预测蛋白质-配体相互作用。ITScore的成对势是从蛋白质数据库中的786个蛋白质-配体复合物结构的训练集中导出的。基于SYBYL软件的原子类型类别,使用了26种原子类型。这种迭代方法规避了在导出基于知识的评分函数时长期存在的参考状态问题。基本思想...
lambda predict protein亚细胞定位-回复 第一步:简介亚细胞定位的重要性和背景 亚细胞定位是研究细胞内蛋白质的位置和运输的关键领域。蛋白质的亚细胞定位对于理解细胞的功能和研究相关疾病具有重要意义。在生物科学领域,了解蛋白质的亚细胞定位信息能够帮助我们更好地理解它们的功能和相互作用。在过去的几十年中,亚细胞定位...
Name: Predict protein Link: http://www.predictprotein.org/ Description: PredictProtein is a service for sequence analysis, structure and function prediction. When you submit any protein sequence PredictProtein retrieves similar sequences in the database and predicts aspects of protein structure and ...
NVDT A new computational method for protein-protein interaction and non-interaction predictions from the gene sequence Part 1:Datasets ---Positive and negative samples of each species. Each .xlsx file has two columns and several rows. Each row represents one protein pair (positive samples are int...