PREDICT-PD is a ground-breaking project using simple tests to identify people at high risk of Parkinson’s disease before the symptoms appear.
PREDICT-PD:An online approach to prospectively identify risk indicators of Parkinson’’s disease. Noyce AJ,R’’Bibo L,Peress L,Bestwick JP,Adams-Carr KL,Mencacci NE,et al. Movement Disorders . 2017Noyce AJ, R'Bibo L, Peress L, Bestwick JP, Adams-Carr KL, Mencacci NE, et al. ...
Subtle motor disturbances in PREDICT-PD participants OBJECTIVE: The PREDICT-PD study aims to identify increased risk of Parkinson''s disease (PD) using online assessments of previously identified risk and early features of PD and an evidence-based scoring algorithm. We sought to determine ... AJ...
High PD-L1 expression (≥50%) is a routine biomarker but is incompletely predictive, with response rates to PD-1 monotherapy only 35-45% in patients with lung cancer. Beyond PD-L1, additional individual pre-treatment variable...
Pornography: How Does the Boomer Generation and Older Predict Others' Viewing Time? 来自 钛学术 喜欢 0 阅读量: 135 作者:S Katie,G Joshua 摘要: The increase of exposure to online pornography has decreased the age of initial exposure to pornography. However, very little is known about the ...
Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancer ArticleOpen access02 June 2022 Background Before the advent of BRAF/MEK targeted therapy and immune checkpoint inhibitors (ICI), metastatic melanoma (MM...
to predict response to anti-PD-1/PD-L1 inhibitors in mUC regardless of the setting (i.e. first-line or post platinum). Methods Study design and patient cohort We identified patients with histologically confirmed diagnosis of mUC treated with an anti-PD-1/PD-L1 agent at Dana-Farber Cancer ...
INTRODUCTION AND OBJECTIVES: PREDICT Prostate is a novel prognostic model that provides individualised long-term prostate cancer-specific and overall survival estimates using baseline clinico-pathological and co-morbidity data. The model, derived from UK data and validated in an East Asian cohort, estima...
To our best knowledge, this study identified the first cirRNA signature to predict survival benefit for advanced melanoma patients treated with immunotherapy. None of these circRNAs have been reported before. Moreover, since we only included the patients treated with anti-PD-1 monotherapy, our ...
IDO activity, expressed as kyn/trp ratio, is associated with response to immunotherapy; in particular, higher kyn/trp ratio could predict resistance to anti-PD-1 treatment. These preliminary results suggest the possibility of using anti-PD-1 plus IDO inhibitor in those patients with high level ...