npj Precision Oncology is a new open-access journal committed to publishing cutting edge scientific research in all aspects of precision oncology from basic science to translational applications, to clinical medicine.
Nat. Rev. Cancer 2, 38–47 (2002). Article CAS PubMed Google Scholar Chan, D. A., Sutphin, P. D., Yen, S. E. & Giaccia, A. J. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1α. Mol. Cell. Biol. 25, 6415–6426 (2005). ...
et al. Personalized medicine for patients with advanced cancer in the phase I program at MD Anderson: validation and landmark analyses. Clin. Cancer Res. 20, 4827–4836 (2014). Article CAS PubMed PubMed Central Google Scholar Schwaederle, M. et al. Impact of precision medicine in diverse...
IMPACT2, TAPUR, NCI-MATCH, DART [for rare cancers]) or for prostate cancer (STAMPEDE). The efficacy of the precision medicine approach was first demonstrated in IMPACT1. That trial deployed tumor molecular profiling to match patients
Precision Medicine Revolutionizing Esophageal Cancer Treatment: Surmounting Hurdles and Enhancing Therapeutic Efficacy through Targeted Drug Therapiesdoi:10.3390/onco3030010STEM cell transplantationESOPHAGEAL cancerDRUG therapyVASCULAR endothelial growth factor receptorsTREATMENT effectiveness...
Genome Medicine is pleased to present a special issue on Precision Cancer Medicine. It explores how genomics is providing a detailed understanding of cancer and how next generation sequencing can aid diagnosis and guide the development of targeted therapies. This collection of articles has not been ...
Precision cancer medicine has the potential to dramatically improve the outcomes of patients with cancer; however, despite the precise nature of the therapies involved, generating reliable evidence of efficacy is often challenging. In this Perspective, t
Here, I briefly portray tumor cell clonal evolution at the cellular and molecular levels, and present the multiple types of genetic heterogeneity in tumors, with a focus on their impact on the implementation of personalized or precision cancer medicine. 展开 关键词: Genetic heterogeneity Clonal ...
are due to the advent of new technology and treatments. Notably, numerous difficulties have been encountered, although each medicine class has its own unique benefits and drawbacks. To serve as a key summary for the development of new treatment options for precision cancer medicine recently, this ...
Genome Medicine (2020) 12:16 https://doi.org/10.1186/s13073-020-0714-y REVIEW The paradox of cancer genes in non- malignant conditions: implications for precision medicine Jacob J. Adashek1†, Shumei Kato2†, Scott M. Lippman2† and Razelle Kurzrock2*† Open Access Abstract Next-...