Precision medicine strategies in oncology: mixed approaches to matched therapies.In the last few decades, precision medicine aroused in oncology as a promising approach to treat patients with molecularly targeted agents, developed to specifically inhibit an abnormally activated molecular target in a ...
The OncLive Precision Medicine in Oncology® condition center page is a comprehensive resource for clinical news and expert insights on precision-focused approaches in patients with cancer, with gene-targeted tyrosine kinase inhibitors and antibody-drug conjugates, checkpoint inhibitors, tumor-infiltrating...
Innovative trial designs (umbrella or basket studies) are emerging as patient-centric approaches and public鈥損rivate partnerships, cross-industry, government and non-profit sector collaborations are enabling implementation. Success will require continued innovation, new paradigms in oncology drug development...
Precision medicine in pediatric oncology: Lessons learned and next steps The maturation of genomic technologies has enabled new discoveries in disease pathogenesis as well as new approaches to patient care. In pediatric oncology... RJ Mody,JR Prensner,J Everett,... - 《Pediatric Blood & Cancer》...
Here, AI combined with multiple different combinations of CpG markers, statistical and bioinformatic approaches yielded high diagnostic accuracy for OC detection with an AUC close to or equal to 1.0. Despite the small number of cases in the study statistical significance was achieved with the lower ...
Until recently the application of artificial intelligence (AI) in precision oncology was confined to activities in drug development and had limited impact on the personalisation of therapy. Now, a number of approaches have been proposed for the personali
- 《Journal of Clinical Oncology》 被引量: 0发表: 2024年 Presentation II: Precision Medicine in migraine management is to present the current therapeutic approaches for migraine treatment and to investigate their applicability, according to the new data of Medical Precision... T Barkoula 被引量:...
In his January 2015 State of the Union address, President Barack Obama announced a new Precision Medicine Initiative (PMI) to personalize approaches toward improving health and treating disease (www.whitehouse.gov/precision-medicine). He... JE Fradkin,MC Hanlon,GP Rodgers - 《Diabetes Care》 被...
Conclusion These results signal that clinical effectiveness of precision oncology approaches will depend on rates of genomics﹊nformed treatment change. Our study will guide future evaluations of precision oncology and support reliable effect estimation when RCT data are unavailable....
The concept of precision oncology involves the prescription of therapies that target the molecular driver alterations of an individual patient’s tumor. This treatment paradigm has been accelerated in recent years through increasing integration of molecular profiling approaches into mainstream clinical oncology...