Pre-clinical and clinical trials for anesthesia in neonates: gaps and future directionsdoi:10.1007/s00247-024-06066-5Literature examining possible deleterious effects of anesthesia exposure on the developing brain has increased substantially over the past 30years. Initial concerning findings in animal ...
neurons that produced dopamine and improved the abnormal behaviors of 6-OHDA-lesioned rats. Two previous clinical trials for PD using PSCs have transplanted ESC-derived neural progenitor cells (NCT02452723) and ESC-derived DA neurons (NCT03119636). These pre-clinical studies are summarized in ...
PubMed and the Cochrane Library with the terms “pre-eclampsia” and “hypertension and pregnancy”, and cross-referenced them with the following terms: “epidemiology”, “defi nition”, “prediction”, “prevention”, “management”, “clinical trials”, “preconception care”, and “...
numerous clinical trials employingPfRAS administered either by mosquito bite,23subcutaneous or intradermal administration,24or intravenous inoculation8,25,26have been carried out. Likewise, the CPS immunization protocol
View PDFView articleView in ScopusGoogle Scholar [18] https://www.sciencedaily.com/releases/2019/03/190331192532.htm Google Scholar [19] https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/cd40-agonistic-monoclonal-antibody-apx005m Google Scholar [20] S. He, H. Zhao, M...
Its primary function is to develop and support cross-sectoral development of new microbicidal agents that specifically address the needs and perspectives of women across the length of the research and development pipeline, including authority to execute all phases of clinical trials of microbicides. It...
Neoadjuvant radiotherapy to facilitate immediate breast reconstruction: a systematic review and current clinical trials. Ann Surg Oncol. 2019;26(10):3312-3320. doi:10.1245/s10434-019-07538-x PubMedGoogle ScholarCrossref 19. Brackstone M, Palma D, Tuck AB, et al. Concurrent...
The study population included patients treated at the University of Texas MD Anderson Cancer Center (MDACC) who participated in the ATTACC screening protocol, a clinical research study that ran from 2010 through 2018 at MDACC (ClinicalTrials.gov identifier:NCT01196130).48This protocol was approved ...
The original protocol registered with the Pan-African Clinical Trials Registry identified three primary outcomes: pre-eclampsia, pre-eclampsia or pregnancy loss before labour at any gestation, and severe maternal morbidity and mortality index: defined as one or more of the specified secondary outcomes....
In clinical trials, ceritinib has demonstrated durable responses and progression-free survival in ALK-inhibitor–pre-treated and –naïve NSCLC patients, including high overall and intracranial response rates in those with central nervous system metastases. Selective gastrointestinal toxicity of ceritinib, ...