β-Galactosidase activities were measured using ONPG as the substrate (the values are mean ± s.d., n = 4 independent assays). Different letters represent significant differences indicated by one-way ANOVA with Bonferroni’s multiple comparisons test (P < 0.05). The exact P values ...
Moreover, class III PPK2 showed broad substrate specificity over purine and pyrimidine bases. This is the first demonstration that class III PPK2 possesses both class I and II activities. 展开 关键词: Bacteria Nucleoside Diphosphate Sugars Substrate Specificity Phosphorylation Phosphotransferases (...
Nonetheless, we did not identify BIN2 as either an interactor or a putative substrate in our unbiased approaches. Interestingly, DYRK1, which also belongs to the CMGC kinase family, possesses a phosphorylated tyrosine within a conserved region similar to the phosphorylated tyrosine region of BIN2....
KO of grp-1, a GEF that stimulates Arf and PIP5K/PPK-1 to increase production of PIP2 substrate for the IIS cascade, provides neuroprotection.Nazila TehraniJohn Del RosarioMoises DominguezRobert KalbItzhak Mano