Conclusions Simvastatin inhibits the cardiac hypertrophy and improves cardiac function. The mechanism of simvastatin on cardiac remodeling and function relates to the increase of PPARγ expression and preventing the NF-κB activation. 展开 关键词: simvastatin rabbit congestive heart failure hypertrophy PPAR...
Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity). ...
The present study was designed to investigate the expression changes of PPAR-alpha, -beta, -gamma and NF-kappa B in the hippocampus of rats with global cerebral ischemia/reperfusion injury (GCIRI) after treatment with agonists or antagonists of PPAR-gamma. Methods A rat GCIRI model was ...
Z Jie,T Schmid,B Brüne - 《Molecular Biology of the Cell》 被引量: 415发表: 2003年 Gliadin stimulates human monocytes to production of IL-8 and TNF-α through a mechanism involving NF-κB Wheat gliadin is the triggering agent in coeliac disease. In this study, we documented that proteol...
Pharmacological activation of PPAR gamma ameliorates vascular endothelial insulin resistance via a non-canonical PPAR gamma-dependent nuclear factor-kappa B trans-repression pathway 文档格式: .pdf 文档大小: 3.14M 文档页数: 11页 顶/踩数: 0/0 ...
omega 3 Polyunsaturated fatty acids (PUFA) inhibit NF-kappa B activity in LPS-Stimulated proximal tubular cells by PPAR gamma activation. 来自 core.ac.uk 喜欢 0 阅读量: 35 作者:H Li,X Ruan,J Moorhead,S Powis,R Fernando,D Wheeler,Z Varghese ...
Sesamol suppresses the inflammatory response by inhibiting NF-kappa B/MAPK activation and upregulating AMP kinase signaling in RAW 264.7 macrophages Sesamol is a lignan isolated from sesame seed oil. Li,Zih-Ying,Fang,... - 《Inflammation Research Official Journal of the European Histamine Research ...
展开 关键词: Endothelium, Vascular Cell Line Humans Thiazoles Thiazolidinediones Prostaglandin D2 NF-kappa B Receptors, Cytoplasmic and Nuclear Transcription Factors RNA, Messenger DOI: 10.1016/S0090-6980(01)00155-1 被引量: 229 年份: 2001 收藏 引用 批量引用 报错 分享 全部...
The cell survival processes associated with apoptosis or necrosis, inflammation, and autophagy [4] involve the peroxisome proliferator-activated receptor-γ (PPAR-γ; apoptosis and inflammation) [5], nuclear factor kappa-B (NF-κB; inflammation) [6], and phosphoinositide 3-kinase (PI3K/AKT; ...