PPARGC1B 基因功能 The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose meta...
实验步骤包括细胞裂解、抗体孵育、免疫沉淀和Western blotting分析,通过检测共沉淀蛋白的条带,评估PPARGC1B与其他蛋白质的相互作用。 报告基因测定(Reporter Gene Assays): 报告基因测定用于评估PPARGC1B的转录共激活功能。通过将PPARGC1B与一个含有特定响应元件的报告基因(如荧光素酶或β-半乳糖苷酶)共转染入细胞,测定...
, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene....
, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene....
PPARGC1BKashin-Beck disease (KBD) is a chronic osteochondropathy. The genetic basis of KBD remains elusive now. To investigate the relationship between PPARGC1B gene polymorphism and KBD, we conducted a two-stage association study using 2743 unrelated Han Chinese subjects. In the first stage, ...
Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. 应用 酶联免疫吸附测定(ELISA),免疫组织化学(IHC) 属性 保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol 运输...
背景资料Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.It is mapped to 5q32.The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors,including estrogen receptor alph...
Rat PPARGC1B shRNA Plasmid的详细介绍 shRNA Plasmid to inhibit PPARGC1B expression by RNA interference. This product contains 3 separate slightly different shRNA sequences which knock down rat PPARGC1B gene specifically. Each vial contains 50 μg of lyophilized shRNA. ...
浓度:450 μg/ml 库存:现货 Size mouseCoIP Andrographolide prevents bone loss via targeting ERRalpha-regulated metabolic adaption of osteoclastogenesis. mouseWB EMBO Rep Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis. ...
Atherosclerosis Supplements Volume 3, Issue 2, October 2002, Pages 105PPARGC1/PGC1 gene locus: Associations with obesity indices and diabetes risk: , H. Oberkofler, V. Linnemayr, B. Iglseder, M. Hedegger, P. Wolfsgruber, B. Paulweber, G. Fastner, F. Krempler, W. Patsch. Landes...