In addition, siRNA-mediated knockdown of E-cadherin expression restored the motility of PGC-1alpha-overexpressing HepG2 cells, indicating that up-regulated E-cadherin is responsible for the lower migratory ability of these cells. Intriguingly, siRNA-mediated silencing of PPARgamma abolished E-cadherin...
经检测验证,可与人、小鼠、大鼠种属来源的PGC-1alpha蛋白发生免疫反应. 保存建议 提供的PGC-1alpha抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该PGC-1alpha抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融. ...
(p< 0.05). Inhibition of PGC1α could inhibit the function of SZ-A to enhance lipid metabolism in hepatocytes. PGC1α might interact with NRF2 to exert MAFLD-remedying effects.Conclusions: By regulating the expression of PGC1α and its interacting KEAP1/NRF2 pathway in mouse liver cells, ...
The nuclear receptor peroxisome proliferator activated receptor-alpha (PPARα) and PPAR-gamma coactivator-1alpha (PGC-1α) play important roles in transcriptional regulation of myocardial metabolism and contribute significantly to the changes that occur in the diabetic heart. This review summarizes the ...
英文名称: PPARGC1A (Peroxisome Proliferator-activated Receptor gamma Coactivator 1-alpha, PGC-1-alpha, PPAR-gamma Coactivator 1-alpha, PPARGC-1-alpha, Ligand Effect Modulator 6, LEM6, PGC1, PGC1A, PPARGC1) (MaxLight 490) 英文同义词: PPARGC1A (Peroxisome Proliferator-activated Receptor gamma...
化学性质安全信息用途供应商1 PPARGC1A (Peroxisome Proliferator-activated Receptor gamma Coactivator 1-alpha, PGC-1-alpha, PPAR-gamma Coactivator 1-alpha, PPARGC-1-alpha, Ligand Effect Modulator 6, LEM6, PGC1, PGC1A, PPARGC1) (MaxLight 490)化学性质 ...
cAMP-dependent protein kinase induction of PPARgamma coactivator-1alpha (PGC-1alpha) and uncoupling protein 1 (UCP1) expression is an essential step in the... G Karamanlidis,A Karamitri,K Docherty,... - 《Journal of Biological Chemistry》 被引量: 182发表: 2007年 Insulin-induced up-regulate...
The nuclear receptor peroxisome proliferator activated receptor-alpha (PPARα) and PPAR-gamma coactivator-1alpha (PGC-1α) play important roles in transcriptional regulation of myocardial metabolism and contribute significantly to the changes that occur in the diabetic heart. This review summarizes the ...
Delta(9)-THC is protective in a cell culture model of Parkinson's disease through a PPAR gamma mediated mechanism resulting in increased expression of PGC1-alpha 来自 ResearchGate 喜欢 0 阅读量: 9 作者:ML Zeissler,O Hanemann,JP Zajicek,CB Carroll ...
The Coactivator PGC1 Cooperates with Peroxisome Proliferator-Activated Receptor a in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty ... Peroxisome proliferator-activated receptor alpha (PPARalpha) plays a key role in the transcriptional control of genes encoding mitochondrial fatty acid...