10. Li Y, Yuan L, Jiang S, Liu S, Xia L, Shen H, et al. Interleukin-35 stimulates tumor necrosis factor-α activated osteoblasts differentiation through Wnt/β-catenin signaling pathway in rheumatoid arthritis. Int ...
表2分化不同时间PPAR信号通路的差异表达基因变化Table 2Changes of differentially expressed gene in PPAR signaling pathway at different differentiation time 3讨论 脂肪酸是机体主要能量来源之一,通过核受体如PPARs、肝脏X受体及各种转录因...
and chemokine-chemokine receptor interaction were significantly enriched in the AI lesions. GSEA demonstrated that the PPAR signaling pathway was significantly weakened in the AI lesions. The mRNA expression levels of PPARA and PPARG were significantly lower in the AI patients (0.336 ± 0.120, 0.253 ...
工程技术2区)上发表了题为“Red raspberry extract (Rubus idaeus L shrub) intake ameliorates hyperlipidemia in HFD-induced mice through PPAR signaling pathway”的文章,文章对红树莓提取物(RRE)对高脂血症小鼠降血脂作用及其机制展开了系列研究。
Abstract:Objective To explore the role of the PPARα/HOXA10 signaling pathway in mediating the effect of adiponectin (APN) for improving endometrial receptivity in a rat model of polycystic ovary syndrome (PCOS). Methods Forty female SD rat models with letrozole-induced PCOS were randomized, with...
TLR-NF-κB信号通路炎症Peroxisome proliferator — activated receptors (PPARs) influence Toll — like receptors (TLRs) —nuclear receptor —κB ( NF —κB) signaling pathway through diverse mechanisms to negalively regulate TLR — NF —κB signaling — mediated inflammalion and immune responses under...
利用转录组学和网络药理学分析研究乙醇紫锥菊通过AMRK和PPAR信号通路对甲状腺功能亢进诱导的氧化应激的改善作用 紫锥菊是一种著名的具有抗氧化特性的植物补充剂。然而,EP对甲状腺功能亢进引起的氧化应激的影响尚未得到研究。本研究旨在采用转录组学和网络药理学分析相结合的综合策略,评估乙醇紫锥菊(EEP)对甲状腺功能亢进...
PPAR signaling pathway overview Like other nuclear receptor super families, PPAR is essentially a class of ligand-dependent transcriptional regulators, all of which are single subunits with an N-terminal region (A/B region), a highly conserved DNA-binding region (C region), and the hormone ...
关键词 白术乙醇提取物;过氧化物酶体增殖物激活受体 γ;小胶质细胞;β 淀粉样蛋白;阿尔茨海默病 Study on the promotion effect mechanism of ethanol extract from Atractylodes macrocephala on microglia phagocytosis and degradation of Aβ based on regulating PPAR-γ signaling pathway CHU Shuang1,WU Yanrao...
将转录组学数据与118个靶基因相交，推测PPAR 信号通路可能是痹宁汤的有效机制。体内实验中痹宁汤治疗后的痛风肾小鼠肾功、尿蛋白有显著改善。这些结果证实痹宁汤主要通过PPAR 信号通路在痛风肾疾病中发挥有效作用。结论：本研究初步预测了痹宁汤治疗痛风肾的主要有效成分、潜在靶点、信号通路，为进一步研究痹宁汤对...