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Semple RK, Chatterjee VK, O’Rahilly S: PPAR gamma and human metabolic disease. J Clin Invest. 2006, 116 (3): 581-589. 10.1172/JCI28003 Article PubMed Central CAS PubMed Google Scholar Yen CJ, Beamer BA, Negri C, Silver K, Brown KA, Yarnall DP, Burns DK, Roth J, Shuldiner AR...
Induction of Differentiation and Apoptosis by Ligands of Peroxisome Proliferator-activated Receptor ?? in Non-Small Cell Lung Cancer The peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand-activated transcription factor belonging to the steroid receptor superfamily. ... TH Chang,E ...
Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic ca... proliferator-activated receptor gamma (PPARgamma) and the effect of PPARgamma activation by its selective ligand on cellular growth in pancreat...
Peroxisome proliferator-activated receptor gamma (PPARɣ) agonists exert powerful anticancer effects by suppressing tumor growth. In this study, we developed PPZ023 (1-(2-(ethylthio)benzyl)-4-(2-methoxyphenyl)piperazine), a novel PPAR ligand candidate, and investigated the underlying signaling path...
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem 2003; 278:498–505. Article CAS PubMed Google Scholar Belfort R, Harrison SA, Brown K, et al. A placebo-controlled ...
We examined the expression of PPARs and the effects of PPARalpha and PPARgamma agonists on growth of mouse and human melanocytes and melanoma cells. PPARal... LL Eastham,CM Howard,P Balachandran,... - 《Current Topics in Medicinal Chemistry》 被引量: 1发表: 2018年 PPARalpha/gamma expressio...
Peroxisome proliferator activated receptor gamma (PPAR gamma) and liver x receptor-alpha (LxR alpha) cooperate in the regulation of inflammation in ... - 《Shock》 被引量: 9发表: 2006年 Autoregulation of the Human Liver X Receptor α Promoter contrast to peroxisome proliferator-activated receptor...
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Genetic association studies are viewed as problematic and plagued by irreproducibility(1). Many associations have been reported for type 2 diabetes(2-17), ... D Altshuler,JN Hirschhorn,M Klannemark...
Recent studies suggest that activation of PPARγ-peroxisome proliferator-activated receptor gamma co-activator 1 alpha (PGC1α) stimulates mitochondrial biogenesis and induces beneficial effects on mitochondrial function in animal models of neurodegenerative disorders including PD, AD, HD (Aguiar Jr, ...