PPAR-gamma is expressed and NF-kB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomas. J Cancer Res Clin Oncol. 2006; 132 :76–84.Vandoros GP, Konstantinopoulos PA, Sotiropoulou-Bonikou G et al (200...
偶联FITCNFKB1 抗体:偶联HRPNFKB1 抗体:偶联PE/ATTO 594NFKB1 抗体:偶联PerCPNFKB1 抗体:偶联RPENFKB1 抗体:偶联StreptavidinOCT4 抗体OCT4 抗体:偶联ATTO 390OCT4 抗体:偶联ATTO 488OCT4 抗体:偶联ATTO 565OCT4 抗体:偶联ATTO 594OCT4 抗体:偶联ATTO 633OCT4 抗体:偶联ATTO 655OCT4 抗体:偶联ATTO 680...
extracellular signal-regulated kinase; GCL, glutamate-cysteine ligase; GSH, reduced glutathione; GR, GST reductase; HSP, heat-shock protein; HO-1, heme oxygenase-1; IKK, IkB kinase; NF-kB, nuclear factor-kB; MAPKs, mitogen-activated protein kinases; Nrf2, NF-E2 related factor 2; NSAIDs,...
细胞核因子p100/p52k基因结合核因子抗体,英文名称:Anti-NFkB p100/p52,保存条件:保存在4℃(短期)或-20℃(长期),形态:Liquid,亚型:IgG等,应用范围:ELISA,WB,IHC,IP,FC,IF等,规格:100ul///200ul,宿主:Rabbit or Mouse等,适用物种:Human,Mouse,Rat等 ...
Cytoplasmic PPARs, by interacting with other transcription factors, such as NF-kB, elicit non-genomic effects by negatively regulating pro-inflammatory gene expression (B) Principal roles exerted by the different PPARs isoforms in skin homeostasis. The resulting complex is able to bind specific ...
The RMSD average values showed the lowest fluctuations for native ligands of the PPAR-γ and NF-KB receptors, while gamma-GluMetSeCys (Se02) had the lowest fluctuations for PI3K receptors. 2.5.2. Solvent-Accessible Surface Area (SASA) Analysis The identification of SASA was carried out to ...
研究人员以一系列与三种蛋白质数值相关的微分方程建立起一个数学模型。 模型中一个主要参数是名叫IkB的蛋白质,它能抑制NF-kB,另一个是有丝分裂原,它是能刺激细胞周期蛋白D形成的浓缩化学刺激物。模型显示,IkB水平高,有丝分裂原水平低时,前脂肪细胞保持蛰伏状态。
CST 3031S Phospho-NF-kB p65 (Ser536) Antibody 100uL CST 3663S CD133 (C24B9) Rabbit mAb 100uL CST 4060L Phospho-Akt (Ser473) (D9E) Rabbit mAb 300uL CST 4257 PI3 Kinase p85 (19H8) Rabbit mAb 100uL CST 4407S Phospho-EGF Receptor (Tyr1173) (53A5) Rabbit mAb 100uL CST 4511S ...
以往研究 认为细菌脂多糖(LPS)能够识别肠道上皮细胞胞浆 受体N0D2/CARD15和N0D1/CARD4,将信号传 递给肿瘤坏死因子受体相关蛋白(TRAF),使之激 活转录因子NF一B,使细胞产生炎症因子级联放大 反应,导致炎症性肠病 ]。目前研究还发现有另外 一个重要核受体PPAR7,在调节肠道炎症中起重要 作用,有可能成为新治疗...
IkB kinase; NF-kB, nuclearfactor-kB; MAPKs, mitogen-activated protein kinases; Nrf2, NF-E2related factor 2; NSAIDs, nonsteroidal anti-inf l ammatory drugs; PPAR,peroxisome proliferator-activated receptor; PPRE, peroxisome proliferatorresponse element; PGs, prostaglandins; PI3-kinase, phosphatidylinos...