How advanced or at what stage a cancer is and its complexity is usually determined by examining microscopically a sample of body tissue with or around the growing tumour, or a biopsy test (in medical terms). The biopsy test determines, first, if the tumour is benign (i.e., non-cancerous...
Overall, these results indicate that our TD-MS workflow is sufficiently sensitive to monitor the incorporation of the i20S, not only in biological models such as cells and organoids, but also in biopsy samples. 3.2. Relative TD Label-Free Quantification of c20S and i20S in Complex Mixtures ...
biopsy material cited above [17] was seen on material obtained by large bore needle biopsy, but was present both in light microscopic sections and on electron microscopy, the latter was seen in tissue fixed with osmolarity-controlled glutaraldehyde. Segmental sarcomere hypercontraction was also found...
Animal genotyping:genotypes of the mice were confirmed by standard polymerase chain reaction analysis of ear-notch biopsy tissue. GoTaq green master mix for genotyping was purchased from Promega (M7123; Madison, WI, USA). Genotyping primers were from Integrated Technologies (Coralville, IA, USA)....