In addition, the cytokine byproduct TGF-尾 activates macrophages to have an M2-like tumor-associated macrophage (TAM) phenotype. Reciprocally, TGF-尾 from TAMs activated RAD18 in TNBC to enhance tumor stemness, forming a positive feedback loop. Inhibition of YAP or TGF-尾 breaks this loop ...
Nature Neurosciencethanks Jose Moron and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. About this article Cite this article Song, Q., Wei, A., Xu, H.et al.An ACC–VTA–ACC positive-feedback loop mediates the persistence of neuropathic pain and...
www.nature.com/cr npg A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis Shuying Shen1, 2, *, Xiaocan Guo1, *, Huan Yan1, Yi Lu4, Xinyan Ji1, Li Li5, Tingbo Liang3, Dawang Zhou6, Xin-Hua Feng1, Jonathan C Zhao7, Jindan Yu7, Xing-Guo Gong2, Lei ...
In Figure 2.76 a negative feedback signal is produced by using a series voltage. If the phase of the series voltage was changed such that the feedback signal augmented the input, then the nature of the feedback loop would become positive. With this positive feedback system the overall gain...
So, there is a positive-feedback loop between p53 and LATS2. What is the functional outcome of the induction of LATS2? Oren and colleagues showed that the abrogation of LATS2 in U2OS cells by stable knockdown promoted the accumulation of polyploid cells after exposure to nocodazole, and this...
A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth. 来自 Nature 喜欢 0 阅读量: 29 作者:Rasola,A.,Fassetta,M.,D Bacco,F.,D'Alessandro,L.,Gramaglia,D.摘要: Overexpressed or activated hepatocyte growth factor receptor,...
Thaw lakes in Nort... KM Walter,SA Zimov,JP Chanton,... - 《Nature》 被引量: 2541发表: 2006年 A chemokine-driven positive feedback loop organizes lymphoid follicles. Lymphoid follicles are B-cell-rich compartments of lymphoid organs that function as sites of B-cell antigen encounter and ...
Self-amplifying loops are also consistent with the waxing and waning nature of many systemic autoimmune diseases, as exemplified by the lupus “flare”. A fundamental aspect of the positive feedback concept in autoimmunity is that once self-tolerance is lost and effector function is generated, ...
Fully-balanced and completely dual-mono in nature, the 600i v2 incorporates Simaudio's proprietary Lynx technology for the elimination of global feedback, as well as the company's M-eVol2 volume control for very precise volume manipulation (down to 0.1 dB) across 530 steps with no signal ...
The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling. 来自 Nature 喜欢 0 阅读量: 40 作者:Li-wei,Dong,Guang-zhen,Yang,Yu-fei,Pan,Yao,Chen,Ye-xiong,Tan 摘要: p28(GANK) (also known as PSMD10 or gankyrin) is a novel oncoprotein that is highly expressed in...