View bio Learn about positive feedback loops. Study the negative, natural, and positive feedback loop definitions with examples, and identify their importance in science. Updated: 11/21/2023 Table of Contents Positive Feedback Loop Definition Positive Feedback Loop Examples How to Identify a Posi...
et al. A positive feedback loop controls Toxoplasma chronic differentiation. Nat Microbiol 8, 889–904 (2023). https://doi.org/10.1038/s41564-023-01358-2 Download citation Received26 April 2022 Accepted07 March 2023 Published20 April 2023 Issue DateMay 2023 DOIhttps://doi.org/10.1038/s41564...
In addition, we have provided strong evidence that the JAK2/STAT3/C/EBPβ-induced IL-6 positive feedback pathway is important for lung cancer cell growth, migration, and invasion, which suggests that the STAT3-C/EBPβ-IL-6 signaling axis plays a crucial role in TAM-mediated lung cancer ...
Fig. 6: HIF2α enhances PVT1 transcription to form a positive feedback regulatory loop. A A schematic diagram of HRE located in the enhancer of PVT1. B The RNA level of PVT1 was significantly reduced in HIF2α-silencing 786-O cells and increased in HIF2α-overexpressing 769-P cells. ...
A positive feedback circuit driven by m6A-modified circular RNA facilitates colorectal cancer liver metastasisKaixuan Zeng, Jianhong Peng, Yue Xing, Linjie Zhang, Peishan Zeng, Weihao Li, Weili Zhang, Zhizhong Pan, Chi Zhou & Junzhong Lin ...
In summary, we reveal a positive feedback loop between the leukemia-initiating fusion protein AML1-ETO and the m6A demethylase FTO in t(8;21) AML. AML1-ETO upregulates the expression of FTO through PU.1; FTO in turn promotes the expression of AML1-ETO by inhibiting YTHDF2-mediated AML...
2) Mouse studies have revealed that a sustained increase in plasma CXCL12 mediates pain chronicity through the positive feedback loop of CXCL12/CXCR4 axis, thereby enhancing the plasticity of spinal pain synapses. 3) SNI induced a dramatic inflammatory immune response in damaged nerve stump and ...
3) Elevated plasma CXCL12 enhances spinal synaptic structural plasticity of pain through positive feedback. View this article's peer review reports Introduction Chronic pain, defined as a debilitating pain lasting at least 3 months or more, impacts about 25% of the global population in all aspects...
This positive feedback loop may be the underlying mechanism by which activating the VTA-BLA-NAc circuit rescues the reward insensitivity induced by chronic stress (Fig. 7A-D). In conclusion, we uncovered a novel positive feedback loop, the VTA-BLA-NAc circuit, that is activated by positive ...
miR-16-5p was able to inhibit EV71 replication by the suppression of the expression levels of the cell cycle regulators, cyclin E1 (CCNE1) and cyclin D1 (CCND1). Taken together, the results show that miR-16-5p is a positive feedback regulator in EV71-induced apoptosis and suppresses viru...