However, 6 of these 9 were also noted to be seropositive for another auto-antibody ( ANA>1:640). Among patients with ILD and articular symptoms consistent with a clinical diagnosis of rheumatoid arthritis, a positive anti-CCP antibody (28 patients) had a strong association with ILD (x2 =...
To study whether stable treatment with DMARDs affects anti-CCP2 antibody levels in patients with rheumatoid arthritis. In this longitudinal observational s... C Wunderlich,I Oliviera,CP Figueiredo,... - 《Seminars in Arthritis & Rheumatism》 被引量: 8发表: 2016年 Bilateral Sacroiliitis in a ...
Objective To examine periodontal disease and periodontopathic bacteria in anti–cyclic citrullinated protein (anti-CCP) antibody–positive at-risk individuals without arthritis. Design, Setting, and Participants This cross-sectional study took place at a teaching hospital from April 27, 2015, to May ...
ObjectiveTo examine how anti–citrullinated protein antibody (ACPA) epitope spreading takes place prior to the onset of clinical rheumatoid arthritis (RA),... Lotte,A.,van,... - 《Arthritis Rheum》 被引量: 244发表: 2011年 Development of the anti–citrullinated protein antibody repertoire prior ...
Kokkonen H, Johansson M, Innala L, Jidell E, Rantapaa-Dahlqvist S (2007) The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden. Arthritis Res Ther 9(3):R56...
Monoclonal antibody homodimers: enhanced antitumor activity in nude mice. Cancer Res. 1993 Jun. 1; 53:2560-5), however, it is not obvious that in-out antibodies can be developed against any antigen or epitope (Kusano et al. Immunocytochemical study on internalization of anti-carbohydrate ...
The authors found that 43.6% of the seronegative (i.e., IgG anti-CCP2− /IgM RF−) RA patients tested positive for one or a combination of ACPA, RF, and anti-CarP autoantibodies. That these patients tested positive for RA-associated autoantibodies suggests that a single autoantibody ...
(anti-CCP) are hallmarks of patients with seropositive RA2. The presence of anti-CCP in patients with seropositive RA has been associated with more persistent inflammation, greater erosive joint damage, more severe clinical manifestations and worse prognosis than those in patients with seronegative ...
An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes Kevan C. Herold, Brian Bundy, S Alice Long … (2019) Type 1 diabetes is a chronic autoimmune disease that leads to destruction of insulin-producing beta cells and dependence on exogenous insulin for survival. Some...
The false-positive rate of HIV screening was associated with antibody titers of RF-IgG, RF-IgM, RF-IgA, and CCP-IgG in RA (P<0.01). Conclusion Immunological factors, including RF and anti-CCP antibody, may influence the screening of HIV by ECLIA, producing false-positive result....