However, 6 of these 9 were also noted to be seropositive for another auto-antibody ( ANA>1:640). Among patients with ILD and articular symptoms consistent with a clinical diagnosis of rheumatoid arthritis, a positive anti-CCP antibody (28 patients) had a strong association with ILD (x2 =...
Patients with rheumatoid arthritis (RA) can test either positive or negative for circulating anti-citrullinated protein antibodies (ACPA) and are thereby categorized as ACPA-positive (ACPA+) or ACPA-negative (ACPA−), respectively. In this study, we ai
Objective To examine periodontal disease and periodontopathic bacteria in anti–cyclic citrullinated protein (anti-CCP) antibody–positive at-risk individuals without arthritis. Design, Setting, and Participants This cross-sectional study took place at a teaching hospital from April 27, 2015, to May ...
+ IgM-, IgG-IgM+, IgG+IgM+, C1q+, HMGB1+, and CP+ from anti-CCP−RF−, anti-CCP+RF+/−, and anti-CCPhiRFhiRA patients and HCs. Comparisons among the study groups were made by performing the Kruskal–Wallis test and Dunn’spost-hoctest. (E) Collective t-SNE of EVs ...
length of time since first detection of islet autoantibody, number of islet autoantibodies detected and presence of symptoms of type 1 diabetes (see Tables1,3,4and5). Ab, antibody; GP, general practitioner; PRN, pro re nata (as needed); Sx, symptoms; T1D, type 1 diabetes. This figure ...
Chemically modified anti-D typing serum is considered to combine the reliability of saline IgM anti-D with the convenience of slide and rapid tube anti-D. This has led to its wide acceptance in modern blood bank practice. False-positives are considered rare and are controlled by the ABO group...
Monoclonal antibody homodimers: enhanced antitumor activity in nude mice. Cancer Res. 1993 Jun. 1; 53:2560-5), however, it is not obvious that in-out antibodies can be developed against any antigen or epitope (Kusano et al. Immunocytochemical study on internalization of anti-carbohydrate ...
Background Rheumatoid factor (RF) and anti-cyclic citrullinated peptide (CCP) antibody tests are often measured at the time of rheumatoid arthritis (RA) diagnosis but may not be repeated and therefore not available in electronic health record (EHR) data; lab test results are unavailable in most...
anti-citrullinated cyclic peptidesautoimmunitypolyautoimmunityrheumatoid arthritisObjective. This study aimed to compare the prevalence and incidence of polyautoimmunity between anticyclic citrullinated peptide antibody (anti-CCP)-positive and anti-CCP-negative patients with rheumatoid arthritis (RA). Methods. ...
Anti -CCP antibodies were detected with the ImmunoscanRA Elisa kit, and RF by nephelometry (Behring). Antinuclear antibodies were detected by IF test on Hep-2 cells (Inova). Anti - ...doi:10.1186/ar1676M BrozikU B?hmJ CsikiA Polgár...