SchrierAutosomal dominant polycystic kidney disease is a challenging disorder to diagnose and treat eff ...doi:10.1038/nrneph.2015.164Schrier RWNature Reviews NephrologySchrier R9 Decade in revie-polycystic kidne disease: Slowingprogression of autosomal dominant polycystic kidney disease [ J ]. Nat Rev Nephrol, 2015, 11(11)...
Polycystic kidney disease is a genetic disorder that causes fluid-filled cysts to grow in the kidneys. At the same time, hydronephrosis is a condition that causes one or both kidneys to become stretched and swollen due to the build-up of urine inside them. Thus, this is the key diff...
Polycystic kidney disease is a genetic disorder in which an individual develops multiplecystsin the kidneys. These cysts cause kidney enlargement, which may damage the kidneys. There are two main types of polycystic kidney disease: they are autosomal dominant and recessive polycystic ...
Polycystic Kidney Disease(also known as Polycystic Kidney Syndrome) (PKD) is a progressive, genetic disorder of the kidneys. It occurs in humans and other organisms. PKD is characterized by the presence of multiple cysts (hence, "polycystic") in both kidneys. The disease can also damage the ...
Autosomal recessive polycystic kidney disease (ARPKD) is a developmental disorder that mainly affects the kidneys and the biliary tract. Affected patients often have massively enlarged cystic kidneys as well as congenital hepatic fibrosis (CHF) characterized by dilated bile ducts and associated peri...
Autosomal dominant polycystic kidney diseaseUrologyNephrologyBackground Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disorder. In most cases, ADPKD similarly affects bilateral kidneys. Case presentation Among the 605 ADPKD patients that were followed up by our ...
Autosomal recessive polycystic kidney disease (ARPKD) is a monogenic disorder that primarily involves mutations in the PKHD1 gene, although rare, atypical forms of ARPKD due to mutations in other genes have recently been described. For years, pediatric n
Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disorder that is caused by mutations in the genes PKD1 and PKD2 encoding polycystin-1 and polycystin-2, respectively. Polycystin-1 and -2 form a complex, interact with several proteins involved in signal transduction ...
The incidence of ADPKD is 1 to 2: 1000 live births unlike ARPKD which is 1:20,000.Autosomal dominant polycystic kidney disease (ADPKD) is generally a late onset multisystem disorder characterized by bilateral renal cysts; cysts in other organs including the liver, seminal vesicles, pancreas, ...
Adult polycystic kidney disease (APKD) is a single-gene autosomal dominant genetic disorder leading to end-stage renal disease (ESRD, meaning kidney failure). It is associated with mutations in at least two genes, APKD1 and APKD2, but diagnosis is mostly by ultrasonography. We propose a ...