Both HMDA-MTX(I) and HMDA-MTX(II) were coupled with poly[ N -(2-hydroxypropyl)methacrylamide] via oligopeptide -GlyGly-, -GlyLeuGly- and -Gly- dl -PheLeuGly- spacers and physico–chemical characterization of the polymer–drug conjugates was performed. The in vitro release of HMDA-MTX(...
A novel approach to increase the stability of liposomal containers via in prep coating by poly[n-(2-hydroxypropyl)methacrylamide] with covalently attached cholesterol groups. Macromol Chem Phys. 2018:219(7):1700508. 39. Alyane M, Barratt G, Lahouel M. Remote loading of doxorubicin into ...
A novel approach to increase the stability of liposomal containers via in prep coating by poly[n-(2-hydroxypropyl)methacrylamide] with covalently attached cholesterol groups. Macromol Chem Phys. 2018:219(7):1700508. 39. Alyane M, Barratt G, Lahouel M. Remote loading of doxorubicin into ...
Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 5: hydrolytically degradable materials. Macroporous hydrogels based on 2-hydroxyethyl methacrylate, 2-ethoxyethyl methacrylate and N -(2-hydroxypropyl)methacrylamide, methacrylic acid and [2-(met... M Pradny,J Michalek,P Lesny,... - ...
N-(2-hydroxypropyl)methacrylamide polymeric prodrugs containing adriamycin bound to polymers via glycylphenylalanylleucylglycine side chains and, in one ca... B Rihova,M Bilej,V Vetvicka,... - 《Biomaterials》 被引量: 307发表: 1989年 The Biocompatibility of Biodegradable Glycine Containing Polyphosp...
Using similar synthetic protocols, the membrane-disrupting methacrylamide random copolymer 6 has been obtained and tested for its antibacterial activity against Gram-negative E. coli and Gram-positive S. aureus bacteria. Copolymer toxicity was estimated in terms of its hemolytic activity. For mole fract...
(Choiet al., 1998). Researchers have recently synthesized a cationiccopolymerusing N-(2-hydroxypropyl)methacrylamide (HPMA) and the cationicmonomerN-[3-(dimethylamino)propyl]methacrylamide (DMAPMA). These copolymers have demonstrated the enhanced stability of the siRNA/poly(HPMA-b-DMAPMA) complexes, ...
poly (glycerol) (5), poly-N-vinylpyrrolidone (6), poly[N-(2hydroxypropyl)methacrylamide] (7) and poly(amino acid)s (8) were investigated (for revie... H Takeuchi,H Kojima,H Yamamoto,... - 《Journal of Controlled Release》 被引量: 268发表: 2001年 Synthesis of Pt, Pd, Pt/Ag and...
Furthermore, new polymers, in addition to the most known N-(2-hydroxypropyl)methacrylamide copolymer (HPMA), polyglutamic acid (PGA) and poly(ethylene ... GPM Veronese - 《Progress in Polymer Science》 被引量: 589发表: 2007年 Characterization of the MODY3 phenotype. Early-onset diabetes cause...
By using lysosomal enzyme (cathepsin B) responsive GFLG as a linker, N-(2-hydroxypropyl) methacrylamide copolymer-paclitaxel-alendronate (HPMA copolymer-PTX-ALN) was synthesized and used as a bone-targeting drug delivery system. In addition, HPMA copolymer-PTX-ALN nanoparticle showed the greatest ...