oryzae. Ras2 appears to play critical roles in the activation of both the cAMP-signaling and Pmk1 MAPK pathways. When Pmk1 is activated by Mst7, it may in turn activate multiple downstream transcription factors because Mst12 is only required for appressorial penetration. Genes regulated by PM...
Phosphorylation of the Pmk1 MAPK was detected by α-pTEpY antibody in the presence of MEKDD. His-tagged proteins were detected with α-His antibody. b. Micrographs to show representative phenotypes of germlings of Δhox7 mutants expressing phosphomimetic alleles of Hox7 incubated on HP surfaces...
A group of dual specificity protein phosphatases negatively regulates members of the mitogen-activated protein kinase (MAPK) superfamily, which consists of... Tanoue,T. - 《J.biol.chem》 被引量: 550发表: 1999年 A Novel MAPK Phosphatase MKP-7 Acts Preferentially on JNK/SAPK and p38α and β...
The results reveal that the pathway of pmk1-like MAPK is not required on the fungal-fungal interactions between A. bisporus and L. fungicola.CollopySchoolPatrickSchoolD.SchoolAmeySchoolRichardSchoolC.SchoolSergeantSchoolMartinSchoolJ.SchoolChallen...
Skb5, an SH3 adaptor protein, regulates Pmk1 MAPK signaling by controlling the intracellular localization of the MAPKKK Mkh1.The mitogen-activated protein kinase (MAPK) cascaddoi:10.1242/JCS.188854Yuki KandaRyosuke SatohSaki MatsumotoChisato Ikeda...
However, Sty1 MAPK was essential for proper Pmk1 deactivation after hypertonic stress in a process regulated by Atf1 transcription factor. These results provide the first evidence for the existence of cross-talk between two MAPK cascades during the stress response in fission yeast.Madrid...
Importantly, the SAPK-dependent down-regulation of Pmk1p through Pyp1p, Pyp2p, and Ptc1p was not complete, and Pyp1p and Ptc1p phosphatases are able to negatively regulate MAPK Pmk1p activity by an alternative regulatory mechanism. Our data also indicate that Pmk1p phosphorylation oscillates ...
Conserved IYT motif participates in binding of Pmp1 phosphatase to Pmk1 MAPK in S. pombe.Almudena SacristánReviriegoMarisa MadridJosé CansadoHumberto MartínMaría Molina
calcineurin play antagonistic roles in Cl(-) homeostasis; rgf1Delta cells showed the vic phenotype (viable in the presence of immunosuppressant and chlorine ion) and were unable to grow in the presence of high salt concentrations, both phenotypes being characteristic of knockouts of the MAPK ...
Interaction between the SEK-1-PMK-1 p38 MAPK and DAF-2/DAF-16 insulin signaling pathways mediating pathogen resistance and longevity in C. elegansKim, Dennis HReinke, ValerieGarsin, Danielle ARuvkun, GaryAusubel, Frederick MLee, Siu Sylvia...