Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma Article 21 July 2021 Landscape of helper and regulatory antitumour CD4+ T cells in melanoma Article 04 May 2022 Distinct antibody cl
Pmel-1 TCR tetramer staining distinguishes the gene dosage of pmel-1 transgene in CD8+ T cells.Yun JiNatalie AbramsWei ZhuEddie SalinasZhiya YuDouglas C. PalmerParthav JailwalaZulmarie FrancoRahul RoychoudhuriEric Stahlberg
Melanoma gp100 Recombinant monoclonal antibody (PMEL/1825R) 黑素瘤gp100重组单克隆抗体(PMEL / 1825R) 品牌:Enzo CAS No.: 储存条件:+4℃ 纯度:– 产品编号 (生产商编号) 等级规格运输包装零售价(RMB)库存情况参考值 ENZ-ABS324-0100 –100 µg–7,980.00–– ...
Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo Int J Cancer, 66 (1996), pp. 470-476 View in ScopusGoogle Scholar 46 AF Kirkin, K Dzhandzhugazyan, J Zeut...
.com Keywords: tyrosinase; gp 100/pmel17; melanoma; helper T cells; ELISPOT; vaccine The recent understanding of the molecular basis of T cell recogni- tion of human tumours has allowed for the development of vaccine trials targeting the induction of antigen-specific, tumour-reactive CD8+ CTL....
【T细胞表位】:细胞表位指被T细胞受体(T-cell receptor /TCR)识别的抗原表位,表位成分为蛋白质降解后的多肽,多存在于抗原分子内部,需要经过抗原递呈细胞(antigen presenting cells /APC)加工后与MHC分子结合成为复合物才能被TCR识别。 【MHC】:主要组织相容性复合体,MHC可以分为经典MHC与非经典MHC两类,经典MHC包括MHC...
Autoimmune vitiligo does not require the ongoing priming of naive CD8 T cells for disease progression or associated protection against melanoma[J]. J Immunol, 2014,192(4):1433-1439. DOI: 10.4049/jimmunol.1302139 . 返回引文位置Google Scholar 百度学术 万方数据 [28] Shi F , Xu Z , Chen H...
In both SKCM and SKCM-metastasis patients, PMEL expression is negatively correlated with the infiltration cells of CD8+ T cells, macrophages, and neutrophils. Programmed cell-death protein 1 just showed response rates ranging from 20% to 40% in patients with melanoma, so it is cri...
2004. Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules. J. Immunol. 172: 2845-2852.Ramakrishna,V,Treml,JF,Vitale,L,Connolly,JE,O’Neill,T,Smith,PA,Jones,CL,He,LZ,Goldstein,...
Results We previously reported that addition of NX-0255 during in vitro treatment of tumor-specific T cells increases the frequency and absolute numbers of less exhausted CD8+ memory T cells, profoundly improving their functionality and ability to control tumor growth following ACT in tumor-bearing ...