When a bond to Cα has been broken, enzymes must also carefully control the fate of the resulting carbanionic intermediate. Structurally, all known pyridoxal 5′-phosphate (PLP)-dependent enzymes are separated into five groups. The largest of these, Type 1, is the aminotransferase group, of ...
The genomes of fifteen protozoan parasites were analyzed for PLP-dependent enzymes. A minimal set of three PLP-dependent enzymes is identified in the orde... B Kappes,I Tews,A Binter,... - BBA - Proteins and Proteomics 被引量: 55发表: 2011年 A subfamily of PLP-dependent enzymes specializ...
Depending of crystallographic structures and topological studies, PLP-dependent enzymes were categorized in to five distinct folds (I-V) (Alexander et al., 1994, John, 1995, Jansonius, 1998) as illustrated in Table 2. The five independent fold types of PLP-enzymes were: Fold type I; Aspartat...
1)PLP-dependent enzymesPLP依赖酶 2)enzyme dependent酶依赖 英文短句/例句 1.Coating Technology of pH and Enzymes Dependent Changkangning Tablets for Colon-specific DeliverypH-酶依赖型肠康宁结肠靶向片的包衣工艺研究 2.dna dependent rna polymerase依赖dna的rna聚合酶 3.RNA-dependent DNA polymerase依赖于RNA...
4) pH and enzymes dependent pH-酶依赖型 例句>> 5) DNA-dependent protein kinase DNA依赖蛋白激酶 1. Objective To investigate the correlation between the expression of DNA-dependent protein kinase (DNA-PK) and hypoxia inducible factor-1α (HIF-1α) induced by irradiation in hypoxic HeLa ...
It is an interesting PLP-dependent enzyme because it acts as both an aminotransferase and a dehydratase, but also because it lacks the conserved active site lysine residue typically observed in PLP-dependent enzymes. We have solved wild-type and mutant crystal structures of this enzyme in which ...
The protein is a symmetrical homodimer with a tertiary structure and active site organisation similar to, but distinct from, those of other PLP-dependent enzymes whose three-dimensional structures are known. The critical PLP-binding lysine of AONS is located at the end of a deep cleft that ...
Threonine aldolases catalyze the pyridoxal phosphate (PLP) dependent cleavage of threonine into glycine and acetaldehyde and play a major role in the degradation of this amino acid. In nature, L- as well as D-specific enzymes have been identified, but the exact physiological function of D-threo...
Vascular repair is considered a key restorative measure to improve long-term outcomes after ischemic stroke. N6-methyladenosine (m6A), the most prevalent internal modification in eukaryotic mRNAs, functionally mediates vascular repair. However, whether c
Depending of crystallographic structures and topological studies, PLP-dependent enzymes were categorized in to five distinct folds (I-V) (Alexander et al., 1994, John, 1995, Jansonius, 1998) as illustrated in Table 2. The five independent fold types of PLP-enzymes were: Fold type I; ...