PLK1 Pathway The loss of PLK1 expression can induce pro-apoptotic pathways and inhibit growth. Search Connection regarding cerebellar granular covering autolysis together with ante-mortem endemic acid-base reputation Posted onOctober 21, 2024 Reply...
2015. Identification of AREG and PLK1 pathway modulation as a potential key of the response of intracranial 9L tumor to microbeam radiation therapy. Int J Cancer 136:2705-2716.Bouchet A, Sakakini N, El Atifi M, Le Clec'h C, Bra€uer-Krisch E, Rogalev L, et al. Identification of ...
To analyze effect of Plk1 in chemotherapy, we constructed two recombinant adenoviral vectors which carry enhanced green fluorescent protein (rAd-EGFP) and Plk1-shRNA (rAd-shPlk1), respectively. Both inhibition of PI3K/Akt signal pathway through PI3K inhibitor LY294002 and targeted depletion of Plk1...
Inhibition of Plk1 represses androgen signaling pathway in castration-resistant prostate cancer. Cell Cycle 2015; 14:2142-8; PMID:25927139; http://dx.doi. org/10.1080/15384101.2015.1041689Zhang Z,Chen L,Wang H,et al. Inhibition of PLK1 represses androgen signaling pathway in Castration- resistant...
Molecularly, by directly binding the promoter, KLF14 functions as a transcriptional activator of PLK1, a polo-like kinase whose overexpression induced excessive reactive oxygen species (ROS) production. Transient knockdown of PLK1 was sufficient to suppress KLF14 overexpression-potentiated endothelial ...
Targeting the PLK1-FOXO1 pathway as a novel therapeutic approach for treating advanced prostate cancerThe forkhead box protein O1 (FOXO1) is considered to be a key tumor suppressor due to its involvement in a broad range of cancer-related functions, including cellular differentiation, apoptosis, ...
Role of PLK1 signaling pathway genes in gastrointestinal stromal tumorsdoi:info:doi/10.3892/ol.2018.9003ChenYehChengYenChenHuangChiangYehChenChaoOncology Letters
In summary, TSA could suppress the progression of LUAD by inducing cell apoptosis and arresting cell cycle, and these were done by regulating CCNA2-CDK2 complex and AURKA/PLK1 pathway. These findings are the first to demonstrate the molecular mechanism of TSA in treatment of LUAD combination ...
Furthermore, CDK1 knockdown suppressed the expression of PLK1, ANLN, and SGOL2. The CDK1-PLK1/SGOL2/ANLN pathway mediating abnormal cell division in the cell cycle might be a critical process in HCC.doi:10.1080/15384101.2020.1749471Ling Li...
PLK1ProliferationTaken together, circRNA_102541 was upregulated in atherosclerosis, and knockdown of circRNA_102541 suppressed cell proliferation while promotedapoptosis of HUVEC cells via miR-296-5p/PLK1. This novel pathway may serve essential roles on the development of atherosclerosis, andcircRNA_102541...