Platinum-based drugs (cisplatin, carboplatin, and oxaliplatin) are widely used therapeutic agents for cancer treatment. Even though the platinum (Pt)-drugs are routinely used clinically, a clear picture of their distribution within tumor tissues is lacking. The current methods to image the ...
We therefore conclude that platinum-based anticancer drugs can enhance the immunostimulatory potential of DCs and decrease the immunosuppressive capability of tumor cells. This dual action of platinum compounds may extend their therapeutic application in cancer patients and provides a rationale for their ...
Platinum-based drugsPolymerdrugsystemReviewTargeted drug delivery systemPlatinum-based (Pt-based) anticancer drugs have been recognised as one of the most effective drugs for clinical treatment of malignant tumors due to its unique mechanism of action and broad range of anticancer spectrum. But, there...
1. Postoperativechemotherapyschemewascombinationchemotherapythat platinum-based. 术后以铂类为主的联合化疗方案。 paper.pet2008.cn 2. Platinum-baseddrugsareusedextensivelyfortreatingcancer,buttheirusecanbelimitedbytoxicitiesandresistance. 铂类药物被广泛用于治疗癌症,但是他们因为毒性和耐药性使用受到限制。
MAPKi-resistant melanoma cells are susceptible to platinum-based drugs We analysed the chemosensitivity of melanoma cells with acquired resistance to BRAF inhibitor (vemurafenib) (R) or combined BRAF and MEK inhibitor (vemurafenib and trametinib) (DR) treatment and of their sensitive (S) counterparts...
Numerous platinum-based drugs have been synthesized over the years, but only a few of them have been clinically approved. Among these, cisplatin has enjoyed the most success and is used either alone or in combinatorial therapy. Cisplatin was first used for the treatment of cancer in humans in...
Hamelers IH, de Kroon AI. Nanocapsules: a novel formulation technology for platinum-based anticancer drugs. 2007;445-53.Hamelers IH, de Kroon AI. Nanocapsules: a novel formulation technology for platinum-based anticancer drugs. Future Lipidol 2007;2:445–53....
eIF3a gene polymorphism and chemo-sensitivity to platinum-based drugs in ovarian cancer 来自 Semantic Scholar 喜欢 0 阅读量: 100 作者:C Zhang,S Zhang,Y Liu,T Yan,Z Yu 摘要: Objective: To investigate the relationship between the eukaryotic initiation factor 3a(e IF3a)polymorphisms and chemo-...
Platinum-based (Pt-based) anticancer drugs have been recognised as one of the most effective drugs for clinical treatment of malignant tumors due to its unique mechanism of action and broad range of anticancer spectrum. But, there are still some limitations such as side effects, drug resistance/...
Lam2, Steve C. F. Au-Yeung1 & Kenneth K. W. To2 Three molecular targeted tyrosine kinase inhibitors (TKI) were conjugated to classical platinum- based drugs with an aim to circumvent TKI resistance, predominately mediated by the emergence of secondary mutations on oncogenic ...