Light chain myeloma (LCM) is an unusual neoplasm accounting for about 18% of all plasma cell myelomas. It is characterized by the absence of a detectable M protein in the serum and urine protein electrophoresis, altered free light chain ratio, bone marrow plasmacytosis and ...
Plasmablastic lymphoma (PBL) can rarely be seen as a transformation from plasma cell myeloma (PCM), especially in late stages of the disease where it portends a poorer prognosis and a different line of management for the patient. When unrelated to PCM, PBL is considered to be a separate ...
Plasmablastic myeloma transformation of light-chain multiple myeloma Plasmablastic transformation of low-grade B-cell lymphomas: report on 6 cases. Am J Surg Pathol. 2013; 37 :272–281.Daniel Martinez, Alexandra Valera... N Pakasticali,GL Hortin,JY Li - 《Journal of Clinical & Experimental ...
All cases of plasmablastic lymphoma and plasmablastic plasma cell myeloma were positive for MUM1/IRF4, CD138, and CD38, and negative for CD20, corresponding to a plasma cell immunophenotype. PAX-5 and BCL-6 were weakly positive in 2/9 and 1/5 plasmablastic lymphomas, and negative in all...
(2009) Remission induction with lenalidomide alone in a patient with previously untreated plasmablastic myeloma: a case report. Clinical Lymphoma & Myeloma, 9, 328-330.SHER T,MILLER K C,LEE K,et al.Remission in-duction with lenalidomide alone in a patient with previ-ously untreated plasmablast...
Vega F, Chang CC, Medeiros LJ, Udden MM, Cho-Vega JH, Lau CC, Finch CJ, Vilchez RA, McGregor D, Jorgensen JL: Plasmablastic lymphomas and plasmablastic plasma cell myelomas have nearly identical immunophenotypic profiles. Mod Pathol 2005, 18(6):806–815. 10.1038/modpathol.3800355 Article...
Treatment is primarily based onlarge B-cell lymphoma- or multiple myeloma-based chemotherapy regimens, and outcomes remain poor. We present an 84-year-old man with an extensive oncologic history who presented with PBL on his right foot ...
PinnixCCShahJJChuangHDoxorubicin-based chemotherapy and radiation therapy produces favorable outcomes in limited-stage plasmablastic lymphoma: a single-institution reviewClin Lymphoma Myeloma Leuk201616312212826795083 PubMedWeb of Science ®Google Scholar ...
Sher T, Miller KC, Lee K, Chanan-Khan A. Remission induction with lenalidomide alone in a patient with previously untreated plasmablastic myeloma: a case report. Clin Lymphoma Myeloma. 2009;9(4):328–30. Article Yanamandra U, Sahu KK, Jain N, et al. Plasmablastic lymphoma: successful man...
distinguished from the immunoblastic variant of diffuse large B-cell lymphoma, classic (body cavity-based) and solid (extracavitary) variants of primary effusion lymphoma, Burkitt lymphoma with plasmacytoid differentiation, and extramedullary plasmablastic tumors secondary to multiple myeloma or plasmacytoma...