We have previously reported markedly elevated plasma levels of membrane lipid peroxidation products (thiobarbituric acid reactive malonyldialdehyde products; TBARS) in never-medicated, first-episode schizophrenic patients. This was associated with a greater severity of negative symptoms at initial presentation...
The biochemical nature of the plasma membrane renders it susceptible to several forms of chemical disruptions (Fig.1a). In the presence of reactive oxygen species (ROS), the oxidation of polyunsaturated fatty acids (i.e., lipid peroxidation) can lead to the release of damaged lipid fragments an...
Membrane phospholipids are a prominent target of oxidants, and vitamin E efficiently prevents lipid peroxidation. Membrane repair involves Ca2+-activated membrane fusion events42,47. Vitamin E may therefore promote repair by preventing the formation of oxidized phospholipids that theoretically might interfere...
为类型‘细胞的’输入论据。 [translate] aIch komme aus china, wohere komen sie 正在翻译,请等待... [translate] amembrane lipid peroxidation 膜油脂过氧化 [translate] apenneability of plasma membrane, and protective enzymes of cucumber plants 质膜的penneability和黄瓜植物防护酵素 [translate] ...
Plasma species were shown to be able to break important bonds in the cell wall (peptidoglycan) structure in Gram positive bacteria13,14 as well as leading to membrane lipid peroxidation in Gram negative bacteria15. This disruption of the outer shell of the cell will lead to leakage of ...
First, the membrane content in cholesterol and linoleic acid decreased whereas lipid peroxidation and spectrin:membrane occupancy increased, all compatible with higher membrane rigidity. Second, phosphatidylserine surface exposure showed a first rapid rise due to membrane cholesterol decrease, followed by a...
Inflammation is increasingly recognized as being of both physiological and pathological importance in the immature brain. Cerebellar pathology occurs in autism, as a neurodevelopmental disorder with genetic and environmental origins. The genesis of this
In addition, exogenous administration of reactive aldehydes such as 4-hydroxynonenal (HNE) and crotonaldehyde (CRA), both plasma membrane lipid peroxidation end products, was shown to activate HSF1. In fact, HNE is the major α, β-unsaturated aldehyde derived from peroxidation of omega-6 ...
How might vitamin E promote membrane repair? Membrane phospholipids are a prominent target of oxidants, and vitamin E efficiently prevents lipid peroxidation. Membrane repair involves Ca2 + -activated membrane fusion events42,47. Vitamin E may therefore promote repair by preventing the formation ...
The above results revealed that REEs inhibited electron transfer from NADH to oxygen in plant plasma membranes, depressed the production of active oxygen radicals, and reduced the formation of lipid peroxides through plasma membrane lipid peroxidation. REEs ions also enhanced the H + extrusion by ...